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Genetic Research in Human Populations

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Genetic Research in Human Populations Which choice is the best definition of "genetic determinism?" A. Genetic testing can determine appropriate treatments for certain health conditions B. Genes are primarily responsible for human traits, including health, behavior, and disease C. Genetic i...

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  • August 29, 2024
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  • 2024/2025
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  • Genetic Research in Human Populations
  • Genetic Research in Human Populations
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Genetic Research in Human Populations
Which choice is the best definition of "genetic determinism?"
A. Genetic testing can determine appropriate treatments for certain health conditions
B. Genes are primarily responsible for human traits, including health, behavior, and disease
C. Genetic information about an individual can foster stigma and discrimination
D. Parents determine the nature of their children through the inheritance of genes

B. Genes are primarily responsible for human traits, including health, behavior, and disease

As of January 2015, the NIH expects investigators to obtain the informed (valid) consent of research
participants in NIH -funded genetic research for broad research use of data and data sharing, even if the
cell lines or specimens are:
A. Identifiable
B. De-Identified
C. From subjects under 18 years of age
D. From subjects over 18 years of age

B. De-Identified

Which of the following statements is accurate in determining subject risk involved in a genetic study:
A. Understanding the purpose and context of a specific study is critical in determining the risk involved
B. Understanding the risks involved in other genetic studies is critical in determining the risk involved in
a new study
C. All genetic studies should be considered no more than minimal risk
D. All genetic studies should be considered greater than minimal risk

A. Understanding the purpose and context of a specific study is critical in determining the risk involved

Investigator A conducts research on emphysema using biospecimens from human subjects. The consent
form indicates that the research will focus exclusively on emphysema. Investigator B wishes to use the
biospecimens for research on lung cancer. Can Investigator B use the specimens for cancer research
without re-consent if the specimens are de-identified?
A. Yes, if the biospecimens are de-identified then the research is no longer considered human subjects
research.
B. Yes, because research with biospecimens is minimal risk.
C. No, the original research subjects must be re-consented for the cancer research.
D. No, because it would be unethical to conduct research that is not consistent with the consent form
the subjects originally signed.

A. Yes, if the biospecimens are de-identified then the research is no longer considered human subjects
research.

Which choice best describes the purpose of most pharmacogenomic research?
A. To evaluate the association between individual genotypes and the safety and efficacy of a particular
drug or class of drugs
B. To evaluate how different racial and ethnic groups respond to certain drugs or classes of drugs

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