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Bioinformatics Foundations Exam Questions and Answers

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Bioinformatics - AnswersThe use of computers, software, and mathematical models to process and integrate biological information from large data sets. Bioinformatics - AnswersIt is essential to all biologists due to its interdisciplinary nature and involvement of cutting-edge technology. genome, e...

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Bioinformatics Foundations Exam Questions and Answers.

Bioinformatics - AnswersThe use of computers, software, and mathematical models to
process and integrate biological information from large data sets.
Bioinformatics - AnswersIt is essential to all biologists due to its interdisciplinary nature
and involvement of cutting-edge technology.
genome, epigenome, microbiome and metabolome - Answersbioinformatics can also be
(4)
bioinformatics - Answersapplication of machine learning, data mining, optimization,
visualization, and simulation to solve biological problems.
bioinformatics - Answersorganization and analysis of large amounts of complex
biological data through creation, optimization, or use of various software.
bioinformatics - Answersdevelopment and application of computational techniques to
study biological information at the molecular and genomic levels.
bioinformatics - Answersaims to solve complex biological problems through computer
science, mathematics, and statistics.
bioinformatics - Answersit aims to achieve modeling of complex biological processes at
the cellular level and gain insights into biological mechanisms from the analysis of large
volumes of data.
October 1990 - AnswersThe Human Genome Project was launched in?
April 2003 - AnswersThe Human Genome Project was completed in?
The Human Genome Project - AnswersIt provided the fundamental information about
the human blueprint.
Microarray and Probes - AnswersRole of bioinformatics in Gene Expression Data
Analysis (2)
Microarray - AnswersA molecular biology experimental paradigm that is extensively
used to decipher the inherent characteristics and functionality of an entire cohort of
gene transcripts on a genome.
Microarray - AnswersIt contains a solid substrate where protein and DNA are printed as
microscopic spots.
The ability to characterize the complete genes using a single microarray chip or plate. -
AnswersMajor strength of microarray.
Probes - AnswersDNA microarray chip may contain short single-stranded
oligonucleotides or large double-stranded DNA strands and they hybridize with the
cDNA samples from the control and the test samples whose identity is unknown.
RNA Isolation, cDNA (probe) generation, labeling of probe, hybridization, imaging and
data analysis - Answersthe microarray process (6)
Gene/Genome Mapping - AnswersIt is involved with the characterization of key
landmarks on the genome.
To create a comprehensive map of the genome of interest and identify landmarks. -
AnswersFundamental aim of genome mapping?
Silico Gene Mapping - AnswersIt uses the publicly available genomic databases to
discover and map genes on the genome.
Sequence Similarity - AnswersIt can help researchers identify candidate genes or
polymorphisms that may predispose individuals to major pathological conditions like
cancer and autoimmune diseases.

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