FinalIExam:INUR2474/INURI2474I(NewI
2024/I2025IUpdate)IPharmacologyI|I
CompleteIGuideIwithIQuestionsIandI
VerifiedIAnswers|IAIGradeI|I100%ICorrect-
IRasmussen
QUESTION
WhichIdrugIclassIshouldIbeIcautionedIwithIsulfaIallergy?
Answer:
Isulfonurea
QUESTION
SulfonylureasIaction/uses
Answer:
IpromoteIinsulinIsecretionIandI‘ItissueIresponseItoIinsulin
QUESTION
SulfonylureasIsx
Answer:
Ihypoglycemia,IweightIgain
QUESTION
Glipizide,IGlyburide,IGlimepirideIPt.IEducation
Answer:
IstartIwithIoneIdose/dayIthenIpossiblyIincreaseItoIBID
doINOTItakeIwithIalcohol
,I
checkIsugarsIonceIorImore
contraindicatedIinIpt.IwithIliverIorIkidneyIdisease
QUESTION
GlyburideI(2ndIgen)
Answer:
ImoreIpotentIthanI1stIgeneration,IfewerIdrugIinteractions,IETOHImayIproduceIdisulfiram-
likeIreaction
QUESTION
WhichImedicationsIhaveIsideIeffectsIthatIincludeIhypoglycemiaIandIweightIgain
Answer:
Iglyburide,Irepaglinide
QUESTION
MeglitinidesI(Glinides)Iactions/uses
Answer:
I‘IinsulinIsecretion,I“IglucoseIproductionIbyIliver
QUESTION
GlinidesIsx
Answer:
Ihypoglycemia,IweightIgain
QUESTION
GlinidesIPt.IEducation
Answer:
,ImoreIshort-acting,ItakeIwithIeachImeal
contraindicatedIinIpt.IwithIliverIdisease
QUESTION
ThiazolidinedionesI(Glitazones)Iactions/uses
Answer:
I“IinsulinIresistance
‘IglucoseIreuptakeI(muscleIandIfat)I“IglucoseIproductionIbyItheIliver
QUESTION
ThiazolidinedionesIsx
Answer:
Ihypoglycemia,IheartIfailure,IbladderIcancer,Ifractures
QUESTION
PioglitazoneISE
Answer:
IupperIrespiratoryIinfection,Iheadache,IhypoglycemiaI(excessIinsulinIpresent),IheartIfailureI(se
condaryItoIfluidIretention),IbladderIcancer,IfracturesI(inIwomen),IovulationI(unintendedIpregna
ncy)
QUESTION
DipeptidylIPeptidase-4InhibitorsI(Gliptins)
Answer:
I‘IincretinsIactivity
“IglucagonIrelease
“IhepaticIglucoseIproduction
QUESTION
, GliptinsIsx
Answer:
Ipancreatitis,IhypersensitivityIreactions
QUESTION
SitagliptinISE
Answer:
Ipancreatitis,IhypersensitivityIreactions
QUESTION
Sodium-GlucoseICo-TransporterI2I(SGLT-2)IInhibitors
Answer:
I‘IglucoseIexcretionIandIinducesIweightIlossIviaItheIurine
QUESTION
Glucagon-likeIPeptide-1I(GLP-1)IReceptorIAgonists
Answer:
I“IBGIbyIslowingIgastricIemptying
stimulatesIglucose-
dependentIinsulinIreleaseIsuppressesIpostprandialIglucagonIreleaseIreducesIappetite
QUESTION
Alpha-glucosidaseIinhibitorsIactions/uses
Answer:
I“IglucoseIabsorptionIinIgut
QUESTION
Alpha-glucosidaseIinhibitorsIsx