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PCB 3233 EXAM 2 PRACTICE QUESTIONS AND ANSWERS
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PCB 3233 EXAM 2 PRACTICE QUESTIONS AND ANSWERS Induced innate immune response - Answer️️ --Inflammation -Leukocytes called into the site of infection -Soluble molecules made and secreted into the blood and brought to the site of the infection Leukocytes in the order to action - Answer️�...

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  • August 29, 2024
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  • 2024/2025
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©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM

UNIVERSITY OF CENTRAL FLORIDA (UCF)



PCB 3233 EXAM 2 PRACTICE
QUESTIONS AND ANSWERS

Induced innate immune response - Answer✔️✔️--Inflammation

-Leukocytes called into the site of infection

-Soluble molecules made and secreted into the blood and brought
to the site of the infection

Leukocytes in the order to action - Answer✔️✔️-1. Neutrophils - Mass
quantities

2. Monocytes

3.Lymphocytes - days later

2 cell type recognition - Answer✔️✔️-1. NK - looking at your own cells

2. Macrophages - looking at pathogen directly

Macrophages - Answer✔️✔️-use toll like receptors and phagocytic
receptors

PAMP - Answer✔️✔️-pathogen associated molecular patterns - on
pathogen

PRR - Answer✔️✔️-pattern recognition receptors - on leukocyte




1

, ©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM

UNIVERSITY OF CENTRAL FLORIDA (UCF)


Are there different receptor used for phagocytosis vs. cytokine
creation and secretion(signalling)? - Answer✔️✔️-yes

What are the 5 cytokines? - Answer✔️✔️-IL-1

TNF-a

IL-6

CXCL8

IL-12

Which cytokines are pyrogens? - Answer✔️✔️-IL-1

TNF-a

IL-6

What do heat cytokines (Pyrogens) lead to? - Answer✔️✔️-Lead to
fever

Which cytokines activate endothelial cells? - Answer✔️✔️-IL-1 and
TNF-a

What does the activation of endothelial cells lead to? - Answer✔️✔️-
Vasodilation and Vascular premeability

NK cells provides an early response for which kind of infection? -
Answer✔️✔️-Viral Infection




2

, ©SOPHIABENNET@2024/2025 Wednesday, August 21, 2024 12:13 PM

UNIVERSITY OF CENTRAL FLORIDA (UCF)


NK recognizes two types of receptors - Answer✔️✔️-Activating
receptors and inhibitory receptors

Activating receptors recognize - Answer✔️✔️-(Stress induced)
activating ligands which leads to apoptosis.

Inhibitory receptors recognizes - Answer✔️✔️-MHC 1 on all nucleated
cells.

1st effector cell - Answer✔️✔️-Resident Macrophages which is
prevalent in connective tissues

CR1 (complement receptor 1) binds to? - Answer✔️✔️-C3b

C3b is degraded by what to become iC3b? - Answer✔️✔️-Factor I

NK cells can detect? - Answer✔️✔️-MHC molecules

Which receptor can recognize both Gram(-) and Gram(+)? -
Answer✔️✔️-Scavenger Receptor A (SR-A)

Which leukocyte would be first out to the sight of infection in mass
quantities? - Answer✔️✔️-Neutrophils

Macrophages Receptors (PRR): - Answer✔️✔️-Mannose Receptor

CR-3

CR-4

Dectin-1


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