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Samenvatting Overzicht interleukines, CD en Ig - Immunologie $5.88
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Samenvatting Overzicht interleukines, CD en Ig - Immunologie

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Overzichtstabellen over de vrijstelling van interleukines, de betrokken receptoren bij signaaloverdracht (CD's) en de verschillende immunoglobulines. Handig document om het overzicht te bewaren tussen alle verschillende CD's, cytokines en interleukines!

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  • August 30, 2024
  • 3
  • 2023/2024
  • Summary
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IFNγ NK activatie monocyten/macrofagen (reciprook) intracellulaire pathogenen
Th1, ILC1, CTL activatie neutrofielen
verhoogde expressie van MHC-II

⇒ bevordert fagocytose en opsonisatie

virale verspreiding verhinderen (paracrien)

polarisatie: Th0 → Th1
isotype switch: IgM → IgG

TNFα monocyten/macrofagen beenmerg: leukocytose, trombocytose, anemie intracellulaire &
Th1, ILC1, Th17 endotheelactivatie: meer adhesiemoleculen extracellulaire pathogenen
NK
⇒ rekrutering van neutrofielen bij inflammatie

maturatie van DC: iDC → mDC

activatie macrofagen

TGFβ iTreg polarisatie: Th0 → Th17 en Treg
isotype switch: IgM → IgA (anti-inflammatoir)

inductie van iTreg bij immuunantwoord

IL-1 monocyten/macrofagen beenmerg: leukocytose, trombocytose, anemie
symptomen: koorts, anorexia, slaperigheid,
algehele malaise
endotheelactivatie: meer adhesiemoleculen

⇒ rekrutering van neutrofielen bij inflammatie

maturatie van DC: iDC → mDC

IL-2 Th1 stimulatie van T-cel proliferatie intracellulaire pathogenen

B-cel activatie & proliferatie door Th

IL-3 rijping van immuuncompetente cellen uit common
myeloid progenitor (CMP)

IL-4 Th2, ILC2 activatie macrofagen, basofielen, eosinofielen extracellulaire pathogenen
(parasieten)
B-cel activatie & proliferatie door Th

polarisatie: Th0 → Th2
isotype switch: IgM → IgE

IL-5 Th2, ILC2 activatie macrofagen, basofielen, eosinofielen extracellulaire pathogenen
(parasieten)
B-cel activatie & proliferatie door Th

IL-6 monocyten/macrofagen beenmerg: leukocytose, trombocytose, anemie
symptomen: koorts, anorexia, slaperigheid,
algehele malaise
acute fase eiwitten: CRP, SAA, complement,
fibrinogeen

⇒ rekrutering van neutrofielen bij inflammatie

B-cel differentiatie en maturatie

polarisatie: Th0 → Tfh en Th17

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