A deficit in the ECF results in an ________ in the reabsorption of bicarb
that stimulates the _________________________ which stimulates further
reabsorption. This leads to metabolic ______________ secondary to
volume depletion. Treatment is volume replacement with
_______________.
- Correct Answer - Increase; renin-angiotensis; alkalosis; Normal Saline
For every _______ that is excreted there is one bicarb reabsorbed into the
blood.
- Correct Answer - Hydrogen
Hydrogen binds with _________ to be excreted from the
__________________.
- Correct Answer - HPO42-; kidneys
,Ammonia (N4) ________ as the urine pH _________________. This is
helpful in _____________ states.
- Correct Answer - Increases; decreases; acidotic
Most is excreted in the urine but the remaining is reabsorbed into the
interstitial fluid of the kidney to substitute for potassium.
- Correct Answer - Ammonia
Pathological consequences of metabolic acidosis: _______________
myocardial contractility, __________ cardiac output, catecholamine
resistant _______tension and ______kalemia
Acidosis from ingestion of acids such as methanol, ethylene glycol, aspirin
- Correct Answer - Keto
Severe diarrhea, Type 2 renal tubular acidosis leads to loss of
____________ which leads to metabolic ___________.
, - Correct Answer - bicarb; acidosis
Chronic Kidney disease and type 1 renal tubular acidosis cause diminished
renal excretion of _________________ which leads to metabolic acidosis.
- Correct Answer - Hydrogen
Treatment for lactic acidosis r/t poor organ perfusion
- Correct Answer - Fluid Resuscitation
First step in evaluating metabolic acidosis is to renew the
_______________.
- Correct Answer - Anion Gap
Anion Gap seen in ketoacidosis, lactic acidosis, or acute/chronic renal
failure. - Correct Answer - High
Anion gap seen in acidosis caused by diarrhea, excess saline
administration, or medication such as NSAIDS, ACEIs, and trimethoprim -
Correct Answer - Normal
Metabolic ____________ is caused by excess bicarb or deficient hydrogen.
Usually accompanied by __________ kalemia.
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