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NURS549 Drexel Pulmonary Drugs Test With Complete Solution
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NURS549 Drexel Pulmonary Drugs TestWith Complete Solution
COPD (chronic obstructive pulmonary disease) - ANSWER A group of lung
diseases that block airflow and make it difficult to breathe.
Asthma - ANSWER inflammation is primary problem
what do we do for pulmonary disorders? - ANSWER reduce inflammation
stimulate bronchodilation
block bronchoconstriction
cough - ANSWER major protective mechanism we have to keep irritants and
debris out of airway
cough receptors - ANSWER located in trachea (smoothe muscle and
cartilaginous rings, incapable of constriction
Goblet cells secrete - ANSWER mucus for protection which trap foreign debri
cilia in lungs - ANSWER The hairlike projections on the outside of cells that
move in a wavelike manner- moves the debri up and toward the mouth
debri greater than - ANSWER
Epinepherine (adrenaline) - ANSWER binds to beta adrenergic 2 receptors &
produces bronchodilation--keeps the bronchi dilated, offers no resistance to
air flow (normal lungs- bronchi are surrounded by epi) sympathetic CSN
parasympathetic innervation - ANSWER comprised of muscarinic receptors
and bursts of acetylcholine as needed to Broncho constrict; at rest there is no
,parasympathetic influence
acetylcholine - ANSWER released in smoothe muscle of bronchi causing
bronchoconstriction
Anticholinergics - ANSWER parasympathetic system/ cholinergic system that
causes bronchoconstriction with lung insult
GI - Slows motility, spasm
Eyes - Dilates pupils *DO NOT GIVE TO GLAUCOMa PTS*
Heart - Increase HR
Resp - bronchodilator (Atrovent)
produces mucous secretion, bronchoconstriction and is designed to protect -
ANSWER anticholinergic
Ipratropium Bromide - ANSWER short acting Atrovent
Anticholinergic- vagally medicated bronchoconstriction
Tiotropium Bromide - ANSWER Spiriva. LAMA (long acting muscarinic agent)
blocks vagally medicated bronchoconstriction
TCA, first generation antihistamines, opiates, antidiarrheal, bladder
antispasmodics - ANSWER anticholinergic effects
Antihistamines - ANSWER block the binding of histamine receptors in the
bronchi- RESCUE TX given after the trigger causes bronchoconstriction
sedating or non-sedating
Histamine - ANSWER Chemical stored in mast cells that triggers dilation and
increased permeability of capillaries.(triggers bronchoconstriction)
, Sedating Antihistamines H1 receptor - ANSWER Diphenhydramine
Meclizine-Antivert or Bonamine
hydroxyzine- Vistaril
Chlorpheniramine- ChlorTrimeton
cross blood brain barrier- some effect on cough; anticholinergic affects
non-sedating antihistamines H2 receptor - ANSWER Fexofenadine (Allegra)
(Des)Loratadine (Claritin)
Cetirizine (Zyrtec)
antihistamine (anticholinergic effects) - ANSWER tachycardia, sedation,
constipation, urinary retention
Leukotriene Receptor Antagonists - ANSWER block either the synthesis of
leukotrienes or the binding to their receptor sites on bronchial smooth
muscle
what blocks bronchoconstriction more specifically on the path of
inflammation than antihistamines? - ANSWER Leukotriene Receptor Agonist
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