Exam (elaborations)
AHN 548 Exam 5 Autoimmune Diseases In Pregnancy Verified Study Solutions
- Course
- Institution
AHN 548 Exam 5 Autoimmune Diseases In Pregnancy Verified Study Solutions
[Show more]
Content preview
AHN 548 Exam 5 Autoimmune Diseases In PregnancyVerified Study Solutions
SLE is classified as having ANS At least 4:
Malar rash
Discoid rash
Photosensitivity
Oral ulcers
Arthritis
Serositis
Renal disorder
Leukopenia (< 4000/μL), lymphopenia (< 1500/μL), hemolytic anemia, or thrombocytopenia (<
100,000/μL)
Neurologic disorder
Positive test for anti-DNA, anti-Smith, or antiphospholipid antibodies
Antinuclear antibodies in high titers
SLE causes ANS -Unknown environmental triggers in genetically predisposed people.
-Some drugs (eg, hydralazine, procainamide,
isoniazid)
-Meds cause a reversible lupus-like syndrome.
SLE in pregnancy ANS 1. May first appear during pregnancy
2. women who have had unexplained 2nd-tri stillbirth
3. fetus with growth restriction
4. preterm delivery
5. recurrent spontaneous miscarriages
are often later diagnosed with SLE.
May worsen immediately postpartum
, SLE complications in pregnancy ANS -fetal growth restriction
-preterm delivery
-Preeclampsia
-congenital heart block due to maternal antibodies (anti-ssa and ssb) that cross the placenta.
-Lupus flare
-increases risk of perinatal mortality.
-maternal thromboembolic disorders. (SLE+antiphospholipid antibodies )
-Neonatal Lupus (10%): Rash, anemia, thrombocytopenia, or leukopenia; tend to resolve when
maternal antibodies disappear.
Treatment during pregnancy ANS Prednisone
Women w/antiphospholipid antibodies alos given aspirin
and prophylactic heparin
Severe, refractory SLE - immunosuppressants
hydroxychloroquine,imuran
Antiphospholipid syndrome diagnosis ANS Arterial or venous thrombosis or specific
pregnancy complications:
1) IUFD>10 WK
2) PTD, PET, IUGR<34 WK
3) ≥3 unexplained, RPL<10 weeks of gestation
AND
Lab evidence of antibodies to proteins bound to anionic phospholipids:
lupus anticoagulants (LA)
and anticardiolipin antibodies (aCL)
anti-beta-2-glycoprotein-1 antibodies
Antiphospholipid Syndrome Management ANS low-dose aspirin (ASA)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Labtech. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79650 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now
