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GI drug cards

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40 drug cards outlining the most important info for each GI disorder. Stomatitis, peptic ulcer disease, appetite stimulant, mucosal protectant, antacids, antiemetics, weight loss, constipation, antidiarrheals, irritable bowel syndrome, antispasmodics, inflammatory bowel disease.

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  • September 1, 2024
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  • 2024/2025
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jma24191
Stomatitis:
• nystatin (oral/swish & swallow)
o Action: binds to fungal cell membrane, allowing leakage of cellular contents
o SE/AR: contact dermatitis, SJS, N/V/D
• acyclovir
o Action: Interferes with viral DNA synthesis
o SE/AR: dizziness, headache, N/V/D, changes in menstrual cycle, renal failure
• tetracycline syrup & minocycline
o Action: Inhibits bacterial protein synthesis at the level of the 30S bacterial
ribosome
o SE/AR: photosensitivity, N/V/D, esophagitis, hepatotoxicity, pancreatitis
o Nursing Considerations: no antacids, iron, or calcium (no milk!)-will ¯
effectiveness. May cause staining of teeth and bones of baby if taken during
pregnancy or given to children under 8

, Peptic Ulcer Disease:
Histamine 2-Receptor Agonists:
• cimetidine
o Action: Inhibits the action of histamine at the H2-receptor site located
primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion
o SE/AR: arrhythmias, constipation, diarrhea, hepatitis, confusion, impotence,
­ susceptibility to pneumonia
o Nursing Considerations: antacids & sucralfate ¯ absorption.
• famotidine
o Action: Inhibits the action of histamine at the H2-receptor site located
primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion
o SE/AR: arrhythmias, constipation, diarrhea, hepatitis, confusion, impotence,
­ susceptibility to pneumonia
Proton Pump Inhibitors:
• omeprazole
o SE/AR: bone loss (long term use), headache, abdominal pain, N/V/D,
hypomagnesemia
o Nursing Considerations: administer once per day before breakfast, teach
patients to perform weight-bearing exercise daily and consume adequate
calcium and vitamin D, do not take with St. John’s wort, food can ¯
absorption
• pantoprazole
o SE/AR: DRESS, SJS, hyperglycemia, if treatment duration ³ 3 months-
hypocalcemia, hypokalemia, and hypomagnesemia. Vitamin B12 deficiency,
bone fracture
Prostaglandin E Analog:
• misoprostol
o Action: Acts as a prostaglandin analogue, decreasing gastric acid secretion
(antisecretory effect) and increasing the production of protective mucus
(cytoprotective effect).
o SE/AR: abdominal pain, diarrhea, N/V, constipation, dyspepsia, flatulence,
miscarriage, menstrual irregularities, uterine cramping
o Nursing Considerations: ­ risk of diarrhea with magnesium-containing
antacids, administer with caution in women with reproductive potential (will
cause spontaneous abortion if pregnancy < 49 days

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