Exam (elaborations)
NR 293 Pharm Exam 1 Questions And Answers Latest Update 2024/2025
- Course
- Institution
NR 293 Pharm Exam 1 Questions And Answers Latest Update 2024/2025
[Show more]
Content preview
NR 293 Pharm Exam 1 Questions And AnswersLatest Update 2024/2025
Pharmacokinetics:
• How do they work?
• How are meds absorbed/distributed?
o Absorption = how the med is getting into the body’s
bloodstream
▪ First pass is gets “check in” to the body in the
liver/intestines. This is helpful because it reduces the
concentration of the drug making it safe before being
redistributed into the systemic system.
• Enteral route = meds are absorbed in the gut
• Those include PO meds (suspension, tablets, caps, etc)
• Parenteral routes = meds that bypass the
liver/intestines
• Those include IV, SQ, IM, sublingual, rectal, etc.
o Distribution: is when protein (like albumin) pick up the drug
and transported around the body. If it’s not carried by the
body then its called a free drug.
• What happens in metabolism?
o Biochemical alterations where the drug is processed/broken
down and made usable via an enzyme system in the liver.
• What is ½ life? Prodgrugs?
o Half-life is de 昀椀 ned as
▪ 50% of the drug being excreted (removed) from the body.
o Prodrug
,• What does excretion mean?
o Removal of the body. Filtered by the kidneys.
, • What does it mean if you have issues with primary organs that
covers those things…
Explain therapeutic index. Wide? Narrow?
• Digoxin/Lithium example of narrow…
• HIGH therapeutic window
o Less monitoring because it is less likely to have an adverse
reaction.
o It is rarely toxic at higher doses.
o Ex: amoxicillin
• LOW therapeutic window
o Requires more monitoring and more likely to have an adverse
reaction
o It is more likely to become toxic with the slightest dose change
o Ex: anticoagulation drugs like Warfarin
Opioids: reversal and sign and symptoms
• Respiratory
• RR < 12BPM
o Give reversal
• CNS
o Fall precaution/fall risk
o Don’t operate heavy machinery.
• GI effects
o For N/V: teach to take meds with food so it does not upset
your stomach
o Constipation: hydration and high 昀椀 ber, ambulate, stool
softener (docusate [colace])
Transdermal Pain Patch [Fentanyl (Duragesic)]
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Schoolflix. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $16.69. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
62890 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now