Furosemide (Loop diuretics) Interactions - ..... ANSWER...-
Anticoagulants (Increased Bleeding)
-Steroids (Increased K Loss)
Digoxin if Hypokalemia is present
2
,K Wasting Diuretic Lab Abnormalities (serum chemistry
abnormalities with K wasting diuretics) -.... ANSWER...-
Hypokalemia
-Hypomagnesemia
-Hypochloremia
-Hyponatremia
-Hyperglycemia
*Hypocalcemia in Loop Diuretics
*Hypercalcemia in Thiazide Diuretics
Mannitol (Osmotic Diuretics) Action -
....ANSWER...Causes water, chloride, potassium, and
water to be excreted through the kidneys
Mannitol (Osmotic Diuretics) Uses - .....ANSWER...-
Prevent Kidney Failure
- Decrease Intracranial Pressure (ICP)
-Decrease Intraocular Pressure (IOP)
-Usually used in an Emergency situation
Mannitol (Osmotic Diuretics) Side effects/adverse
reactions - ....ANSWER...-GI upset
-Fluid and electrolyte imbalance
-Pulmonary edema from rapid shift of fluids
3
, -Tachycardia
-Rapid Fluid Loss, Acidosis
(Extreme Caution: Heart disease, Heart Failure, and Renal
Failure)
Spironolactone (Potassium-Sparring Diuretics) Action -
....ANSWER...-Blocks Aldosterone
-Because of blocking aldosterone the renal tubules
promote sodium and water excretion and potassium
retention
-Hypotension, Orthostatic Hypotension
-Fluid and electrolyte imbalance
-Photosensitivity
-Hyperkalemia
4
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