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Immunology BOC Midterm Exam Questions And Verified Complete Solutions. $9.99   Add to cart

Exam (elaborations)

Immunology BOC Midterm Exam Questions And Verified Complete Solutions.

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  • Course
  • Boc serology immunology
  • Institution
  • Boc Serology Immunology

Antinuclear antibody tests are performed to help diagnose - Answer lupus erythematosus In the anti-double-stranded DNA procedure, the antigen most commonly utilized is - Answer Crithida lucilia Sera to be tested for IFA-ANA 6 days after drawing is best stored at - Answer 5 +/- 2 A...

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  • September 4, 2024
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  • Questions & answers
  • Boc serology immunology
  • Boc serology immunology
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Immunology BOC Midterm Exam
Questions And Verified Complete
Solutions.
Antinuclear antibody tests are performed to help diagnose - Answer lupus erythematosus



In the anti-double-stranded DNA procedure, the antigen most commonly utilized is - Answer Crithida
lucilia



Sera to be tested for IFA-ANA 6 days after drawing is best stored at - Answer 5 +/- 2



Antibodies directed at native DNA are most frequently associated with which pattern of fluorescence in
the IFA-ANA test - Answer rim



The technologist observes apparent homogenous staining of the nucleus of interphase cells while
performing an IFA-ANA, as well as staining of the chromosomes in mitotic cells. This result is - Answer
expected for anti-DNA antibodies



The result of anti-nuclear antibody test was a titer of 1:320 with a peripheral pattern. Which of the
following sets of results best correlate with these results - Answer anti-dsDNA titer 1:80, and a high
titer of antibodies to Sm



Systemic lupus erthematosus patients often have which of the following test results - Answer high
titers of DNA antibody



Systemic lupus erythematosus patients with active disease often have which of the following test results
- Answer marked decrease in serum CH50



Which of the following is decreased in serum during the active stages of systemic lupus erythematosus -
Answer complement (C3)

,A positive ANA with the pattern of anticentromere antibodies is most frequently seen in patients with -
Answer CREST syndrome



In the indirect fluorescent anti-nuclear antibody test, a homogenous pattern indicates the presence of
antibody to - Answer DNA



In the indirect fluorescent anti-nuclear antibody test, a speckled pattern may indicate the presence of
antibody to - Answer Sm



A patient has the following test results:

ANA + (1:320), ASO 50 Todd units, Complement decreased, RA +

The above results could be seen in patients with - Answer lupus erythematosus



Autoantibodies in the absence of Sm are found in patients with - Answer mixed connective tissue
disease



Which of the following is the most sensitive and appropriate method for the detection of rheumatoid
factor - Answer nephelometry



Rheumatoid factor reacts with - Answer gamma globulin-coated particles



A consistently and repeatedly negative IFA-ANA is - Answer strong evidence against untreated SLE



Positive rheumatoid factor is generally associated with - Answer hyperglobulinemia



The following results are from a rubella titer performed on acute and convalescent sera using a 2-fold
serial dilution

Date tested 1/23/04, Acute serum titer 1:8, Convalescent serum titer 1:32

After evaluating the above results, the best interpretation is - Answer results are consistent with active
infection with rubella

, Rheumatoid factors are immunoglobulins with specificity for allotypic determinants located on the -
Answer Fc fragment of IgG



Rheumatoid factor in patient's serum may cause a false - Answer positive test for the detection of IgM
class antibodies



Rheumatoid factors are defined as - Answer autoantibodies with specificity for the Fc portion of the
immunoglobulin (IgG) molecule



Tissue injury in systemic rheumatoid disorders such as SLE is thought to be caused by - Answer
deposition of immune complexes



False-positive rheumatoid factor in agglutination and nephelometric methods can be due to elevated
levels of - Answer C1q



An acute phase protein that binds to the membrane of certain microorganisms and activates the
complement system is - Answer C-reactive protein



High titers of antimicrosomal antibodies are most often found in - Answer thyroid disease



Which of the following is an organ-specific autoimmune disease - Answer Addison disease



In chronic active hepatitis, high titers of which of the following antibodies are seen - Answer anti-
smooth muscle



In primary biliary cirrhosis, which of the following antibodies are seen in high titers - Answer
antimitochondrial



Anti-RNA antibodies are often present in individuals having an anti-nuclear antibody immunofluorescent
pattern that is - Answer nucleolar

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