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Immunology – MLS Comprehensive Exam Questions 100% Well Answered.
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2) In the anti-double-stranded DNA procedure, the antigen most commonly utilized is: A) rat stomach tissue B) mouse kidney tissue C) Crithidia luciliae D) Toxoplasma gondii - Answer C 9) Systemic lupus erythematosus patients with active disease often have which of the following test resul...

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  • September 4, 2024
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  • 2024/2025
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Immunology – MLS Comprehensive
Exam Questions 100% Well Answered.
2) In the anti-double-stranded DNA procedure, the antigen most commonly utilized is:

A) rat stomach tissue

B) mouse kidney tissue

C) Crithidia luciliae

D) Toxoplasma gondii - Answer C



9) Systemic lupus erythematosus patients with active disease often have which of the following test
results?

A) high titers of antimicrosomal antibodies

B) high titers of antimicrosomal antibodies

C) marked decrease in serum CH50

D) decreased serum immunoglobin levels - Answer C



10) Which of the following is decreased in serum during the active stages of systemic lupus
erythematosus?

A) anti-nuclear antibody

B) immune complexes

C) complement (C3)

D) anti-DNA - Answer C



11) A positive ANA with the pattern of anticentromere antibodies is most frequently seen in patients
with:

A) rhematoid arthritis

B) systemic lupus erythematosus

C) CREST syndrome

D) Sjugren syndrome - Answer C

,12) In the indirect fluorescent anti-nuclear antibody test, a homogenous pattern indicates the presence
of antibody to:

A) RNP

B) Sm

C) RNA

D) DNA - Answer D



13) In the direct fluorescent anti-nuclear antibody test, a speckled pattern may indicate the presence of
antibody to:

A) histone

B) Sm

C) RNA

D) DNA - Answer B



14) A patient has the following test result:

ANA: +, 1:320; ASO: 50 Todd units; Complement: decreased; RA: +

The above results could be seen in patients with:

A) rheumatic fever

B) rheumatoid arthritis

C) lupus erythematosus

D) glomerulonephritis - Answer C



15) Autoantibodies in the absence of Sm are found in patients with:

A) mixed connective tissue disease

B) systemic lupus erythematosus

C) Crohn disease

D) multiple myeloma - Answer A

, 24) Tissue injury in systemic rhemautic disorders such as systemic lupus erythematosus is thought to be
caused by:

A) citotoxic T cells

B) IgE activity

C) deposition of immune complexes

D) cytolytic antibodies - Answer C



25) False-positive rheumatoid factor in agglutination and nephelometric methods can be due to elevated
levels of:

A) cryoglobin

B) histidine-rich-glycoprotein

C) aspartame

D) C1q - Answer D



26) An acute phase protein that binds to the membrane of certain microorganisms and activates the
complement system is:

A) C-reactive protein

B) tumor necrosis factor alpha

C) neutrophils

D) Kinins - Answer A



28) Which of the following is an organ-specific autoimmune disease?

A) myasthenia gravis

B) rheumatoid arthritis

C) Addison disease

D) progressive systemic sclerosis - Answer C



30) In primary biliary cirrhosis, which of the following antibodies is seen in high titers?

A) antimitochondrial

B) anti-smooth

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