(HU) NSG 124 Pharmacology - Knowledge Test 1 Guide

NSG 124



Pharmacology




KNOWLEDGE TEST 1




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,1. What is the primary mechanism of action for beta-blockers in
managing hypertension?
A. Decreasing heart rate
B. Vasodilation
C. Increasing renal blood flow
D. Inhibition of aldosterone
Correct Answer: A. Decreasing heart rate
Rationale: Beta-blockers primarily reduce heart rate and
contractility, leading to decreased cardiac output, which effectively
lowers blood pressure.


2. Which of the following medications is a potent inhibitor of
CYP3A4?
A. Omeprazole
B. Ketoconazole
C. Ranitidine
D. Metformin
Correct Answer: B. Ketoconazole
Rationale: Ketoconazole is a known strong inhibitor of CYP3A4,
which can increase the plasma concentrations of drugs metabolized
by this enzyme.
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, 3. Which class of drugs is primarily used to manage lipid levels in
patients with hyperlipidemia?
A. ACE inhibitors
B. Statins
C. Beta-blockers
D. Anticoagulants
Correct Answer: B. Statins
Rationale: Statins are the first-line treatment for hyperlipidemia
as they effectively lower LDL cholesterol levels.


4. In patients taking warfarin, which test is regularly monitored to
ensure safe anticoagulation levels?
A. PROTHROMBIN TIME (PT)
B. Hemoglobin A1c
C. Creatinine clearance
D. Liver function tests
Correct Answer: A. PROTHROMBIN TIME (PT)
Rationale: PT, often reported as INR, is critical for monitoring
the anticoagulant effect of warfarin.




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