Exam (elaborations)
MCBM 1- (6) Enzyme, Kinetics, and Regulation (MCBM) Questions with 100% Correct Answers
- Course
- Institution
MCBM 1- (6) Enzyme, Kinetics, and Regulation (MCBM) Questions with 100% Correct Answers
[Show more]
Content preview
1 of 20Term
How can enzyme activity be regulated?
Give this one a try later!
, 1) Genes can impact enzyme concentration
2) Enzymes can interact with inhibitors, allosteric interactions,
and feedback controls
3) The physical structure of the enzyme can be changed via
phosphorylation/dephosphorylation or zymogen activity
Statin competes with HMG-CoA for the active site for HMG-CoA
reductase.
Inhibitor reduces cholesterol levels in the blood because the
competitive inhibitor will take over the cholesterol binding spot.
Binds to a different spot from the active site.
DOES NOT EFFECT THE BINDING OF THE SUBSTRATE TO THE
ENZYME!
Will inactive catalysis
Vmax is decreased, Km decreases (affinity increases).
This is because unbound and bound enzymes exist in equilibrium.
When bound enzymes are essentially "removed" from the equation,
there will be a natural drive to balance this out by binding more
substrate to enzyme.
Don't know?
, 2 of 20
Term
How can competitive inhibition be applied to a clinical scenario?
Give this one a try later!
Only binds to ES complex! Once it does this it will inhibit the catalytic
ability of the enzyme-substrate complex.
Statin competes with HMG-CoA for the active site for HMG-CoA
reductase.
Inhibitor reduces cholesterol levels in the blood because the
competitive inhibitor will take over the cholesterol binding spot.
1) Genes can impact enzyme concentration
2) Enzymes can interact with inhibitors, allosteric interactions, and
feedback controls
3) The physical structure of the enzyme can be changed via
phosphorylation/dephosphorylation or zymogen activity
Km will stay the same since the substrate binding is not changed.
Vmax will decrease since it stops catalysis!
Don't know?
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller codersimon. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $8.00. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
73314 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now