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Exam (elaborations)

MCBM 2 - Neurulation Questions with 100% Correct Answers

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MCBM 2 - Neurulation Questions with 100% Correct Answers

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September 4, 2024
Number of pages
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Written in
2024/2025
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1 of 96

Definition



sources of mesoderm in embryo



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epithelium of alimentary (GI) canal; parenchyma (functional cells) of pancreas
and liver; thyroid, parathyroid; thymus; lung and trachea; middle ear epithelium;
urinary bladder and urethral epithelium; vaginal epithelium

, thicker than the original ectoderm, has a layer of actin filaments at the apical
surface that start contracting to initiate neural folding, causing the cells to take
on a pyramidal shape




dermamyotome layer of the somites




extra embryonic mesoderm from epithelium lining the yolk sac, secondary
mesoderm of gastrulation comes from the primitive streak, and secondary
mesoderm from neural crest cells


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2 of 96

Definition



how are muscle fibers formed?



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failure of formation of lamina and spine in lower thoracic / upper lumbar
vertebral column, causing herniation of dura and sometimes spinal cord




extra embryonic mesoderm from epithelium lining the yolk sac, secondary
mesoderm of gastrulation comes from the primitive streak, and secondary
mesoderm from neural crest cells




epithelium of alimentary (GI) canal; parenchyma (functional cells) of pancreas
and liver; thyroid, parathyroid; thymus; lung and trachea; middle ear epithelium;
urinary bladder and urethral epithelium; vaginal epithelium

, migrating myoblasts reach their destination then fuse to form a primary
myotube which starts growing and incorporating fetal myoblasts to
become a secondary myotube which eventually becomes a mature
skeletal muscle fiber which incorporates satellite cells when repair is
needed


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3 of 96

Definition




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IMAGE 5 IMAGE 2




IMAGE 12 IMAGE 13


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, 4 of 96

Definition



what happens to the original endoderm



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hypoblast - replaced by mesodermal cells; endoderm form epithelial
surfaces, but the supporting elements of any given organ are derived from
its mesoderm




neural folds come together and fuse (above the fusion point becomes
prosencephalon, below the spinal cord) - neural groove is now the neural tube,
space inside the neural tube is the neural canal




mesoderm - forms the skeletal and muscular systems




ectoderm - develops into the outer layer of the skin


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5 of 96

Definition



what does the neural crest give rise to?



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