MIP 260 Test 1 Questions with All
Correct Answers
Clinical signs of african sleeping sickness - Answer-chancre at bite site, intermittent
fever, headaches, extreme fatigue, progressive confusion, personality chnages, swollen
nodes at the abse of the skull
Varient surface glycoprotein coat - Answer-vsg covers the entire organism (a barrier to
antibodies), osicallte between being VSG+ and -, evades the immune system
Clinical signs of chagas disease - Answer-acute form- small red nodule, lymph node
swelling, chills, muscle and bone pain, enlarged liver and spleen, cardiac failure,
common and sever in children
chronic form- central nervous system dysfunction, enlarged esophagus and colon,
cardiac failure
leishmania - Answer-heteroxenous, over 23 species and subspecies, sandfly vector,
arthropod vector - promastigote (infectious), amastigotes in vertebrate tissue (humans,
dogs, and rodents), smallest nucleated cells known in this stage
wjat is one of the most puzzling immunological questions - Answer-how leishmania lives
inside macrophages
leishmania life cycle - Answer-sandfly rakes a blood meal, promastigote phagocytize by
macrophages, transforms into amastigote, sandfly rakes a blood meal, transforms into
promastigote, repeat
cutaneous form of leishmania - Answer-topical and major and mexicana, cutaenous
ulcers, small red pauple but then a thin crust develops over the ulcer, can coalesce into
a sore, can heal but will leave large depressed unpigmented scars, secondary infections
are common, dry lesions can persist for months
diagnosis of leishmanaia - Answer-scraping from edge of ulcer and then stained
mucocutaenous form of leismania - Answer-braziliensis, central mexico and norther
argentina, flat ulcerated plaques
visceral form of lesihmania - Answer-amastigotes found in every tissue and body fluid,
incubation of 10d to a year, post kala-azar develops in some cases of inadequate
treatment, wasting and anemia, fever and malaise, enlarged psleen and liver
, order retortamonadida - Answer-two species common in humans, harmless
commensals that are often mistaken for pathogenic species
sprionucleus meleagridis - Answer-parasit eof young galliforms, us uk and south
america, caused 1 million dollar loss in turkeys prior to 1950
other facts about spironucleus meleagridis - Answer-elongate organisms, four pairs of
flagella, a disease of the young animals, adults are the host nut are asmptomatic,
symptoms include dull appearance frothy yellow diarrhea ruffled feathers, treatment us
unsatisfactor
treating spironucleus meleagridis - Answer-treatment is unsatisfactory but prevention is
possible with management and sanitation, separation of chicks and adults is essential
order trichimonadida - Answer-anterior tuft of flagella, stout median rod or axostyle and
undulating membrane, jerky twisting locmotion, found in intestine and reproductive
tracts, do NOT make cysts
the figures of human infections and death per year has not changed in __ years even
though the population has __ - Answer-50, doubled
money for control efforts is scarce because - Answer-pharmaceutical companies are
hesitant to spend money developing drugs for people who cannot pay for them and
there may be more pressing financial problems in less developed countries
how many kids in the us are infected with worms - Answer-55 million (underestimate if
pinworm is included
common opportunistic infections in individuals with aids - Answer-toxoplasma and
cryptosporidium
what are the important, yet subtle effects of parasites - Answer-financial loss and impact
on productivity
primary killers of humans - Answer-parasitism and nutritional deficiencies
parasites that have killed many - Answer-malaria, schistosomiasis, and african sleeping
sickness
also fleas and obligate symbiont bacteria
first systematic appraoach to measure the impact of human parasitism by helminths -
Answer-"This Wormy World" by Stoll
the de-wormed world - Answer-eric loker, 2013, to highlight the dramatic reductions in
the case of human helminthiasis we are likely to see in the future
