Dit zijn aantekeningen van de colleges van de Minor Challenges in Women and Child Healthcare van geneeskunde aan de Vrije Universiteit Amsterdam. De aantekeningen bestaan uit opmerkingen van de lesgevende artsen, belangrijke teksten uit de presentaties en ook beeldmateriaal uit de presentaties. De ...
WEEK 1 2
General introduction 2
Minor introduction 3
Development of the female internal reproductive organs 3
Practicum Excursion 3D Atlas 4
Werkcollege 1: MRKH syndrome 4
Werkcollege 2: AVIRA-syndroom 7
Uterus transplantation 8
Uterus anomalies 10
HTDM - IVF gestation 14
DSD 17
WEEK 2 25
Cesarean section defect (niche) 25
Treatment of the niche 26
De Groene OK 27
Implementation of new techniques: look before you leap 27
Uterine fibroids 29
Fertiliteit 33
Mocellation consideraties 33
WEEK 4 53
Young pregnancy 53
Shock! Etiology and treatment 56
Treatment of shock 57
Extra uterine pregnancies 58
Treatment of EP 61
Miscarriage 64
Anatomy 66
, Screening, diagnosis and management of the early and late growth restricted fetus 76
Long term outcome of FGR and prematurity & the metabolic syndrome 78
Strider - lessons learned 79
Pregnancy complications and later life 80
Management and prognosis of hypertensive disorders and FGR 81
Week 6 83
Perinatal mortality & perinatal audit 83
Asphyxia: neurological aspects and outcome 84
Overview preterm birth 85
Extreme prematurity 87
Prematurity - Long term outcome 88
WEEK 7 93
Obstructed labour 93
The cesarean section 99
Asphyxia - Etiology and Fetal monitoring 101
Asphyxia - Pathophysiology and treatment 107
Practicum: Neonatale reanimatie en medische aspecten intubatie 112
WEEK 8 115
Machine Learning for Health 115
Neonatology and data-analytics 119
WEEK 1
General introduction
Who can be your supervisor?
Staff member (PhD of MD) VUmc or VU or other university medical
central/university/academic research institute.
Tips and tricks contacting supervisors
- Head of department/chef de clinique
- Principal investigator/medical specialist
- (Senior) Researchers
- Postdoctoral researchers/ANIOS/AIOS
- PhD candidates (AIO,OIO)
2
,Minor introduction
Development of the female internal reproductive organs
- Rekenen zwangerschap vanaf eerste dag van menstruatie
3D Atlas of Human Embryology
Adope pdf reader installeren
Urogenitaal
Wolffian duct = mesonephric duct → eerst buis die gaat ontwikkelen
- Belangrijk voor mannelijke anatomie
Müllerian duct = paramesonephric duct
Belangrijk voor vrouwelijke anatomie
- cervix
- bovenste ⅓ deel vagina
- eierstokken
- uterus
3
, Schild (ectoderm) → huid + neurale systeem
Binnenbekleding (endoderm)
Alles tussen schild en binnenbekleding (mesoderm)
Practicum Excursion 3D Atlas
Notochord/chorda signaalmoleculen maken dat de neurale buis en wervelkolom ontstaan.
Kikkers en kippen embryo’s hebben ronde chorda. Dit wordt ook zo weergeven in de meeste
atlassen, terwijl de menselijke embryo’s geen ronde chorda hebben. Hieruit zien we dat de
boeken ook zijn gebaseerd op dierlijke embryo’s.
Werkcollege 1: MRKH syndrome
= Aangeboren afwezigheid baarmoeder en bovenste deel vagina.
- Etiology largely unknown
❖ Regression of Mullerian tract
❖ In males because of testicular AMH
Samensmelten bij buis van müller gaat ergens niet goed. Distale deel van de vagina wordt
gevormd door urogenitale sinus, waardoor distale deel van de vagina wel bestaat.
● Classificatie: anatomical disorder
● External genitalia: female, vaginal aplasia
● Internal genitalia: no uterus, normal ovaries
● Endocrinology: normaal hormonaal patroon, baarmoeder dus secundaire
geslachtskenmerken ook.
● Diagnose: worden niet ongesteld, primaire amenorroe. I.e. no period on the age of 16
or 5 years after menarche.
4
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