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PHCY220 - Cases Exam Study Guide

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  • September 4, 2024
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  • PHCY220 - Cases
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PHCY220 - Cases Exam
Study Guide
First line treatment for AD - Answer Emollients

Hydrocortisone for mild AD which should be applied 1-2x daily

Hydrocortisone butyrate is used for moderate-severe cases and is used if the patient is
unresponsive to HC

Why do AD patients need emollients - Answer Because emollients reduce water loss
across the skin and hydrate the skin to improve barrier function

What are the presentations of AD - Answer Dry itchy rash swollen red skin

Skin may blister or crust or flake off

What strength does HC and HC butyrate come in - Answer HC - comes as 0.5% or 1%
cream

HCB - comes as 0.1% ointment, cream or lotion

Second line treatment for AD - Answer Topical pimecrolimus is used for mild-moderate
cases and tacrolimus is used for moderate-severe cases and is not allowed for children
under 16

Apply these bd for a max of 6 weeks

What are the strengths of pimecrolimus and tacrolimus - Answer P - 1% cream

T - 0.1% ointment

Presentation of psoriasis - Answer Scaling inflammation and redness around the scales,
scales are whitish silver and develop in thick red patches

First line treatment for psoriasis - Answer Calcipotriol for plaque psoriasis and has long
term usage for patients that are not responding to HC

This is appled bd with a max of 100g weekly

HC and HCB like AD

What strength does calcipotriol come in - Answer 0.005% ointment

Second line treatment for psoriasis - Answer Combination of calcipotriol +

, betamethasone dipropionate ointment/gel or foam

Pimecrolimus or tacrolimus can be used short-term under supervision; max of 4 weeks

Presentation of nappy rash - Answer Redness swelling initially scaly which progresses
to erosions

Treatment for nappy rash - Answer HC to the affected area 1-2x daily - max of 7 days

Treatment for urticaria - Answer Antihistamines

Presentation for urticaria - Answer Raised red bumps or welts on the skin

Spots can be blotchy and can be largely connected

First line treatment for acne - Answer Benzoyl peroxide which is applied od and
removed after 2 hours for 3 days, then applied od at night time for 3 days; apply bd if
necessary

Adapalene can also be used for smaller areas which should be applied od in the
evening; review the treatment after 3 months

Second line treatment for acne - Answer These are oral formulations that can be used
after 2 months of first line treatment

Doxycycline which is given as a 100mg tablet and patients can take 50-100mg od

Minocycline is also available as 100mg capsules or 50mg tablets - this is given 100mg od
in 1-2 doses

Third line treatment for acne - Answer Isotretinoin is reserved for patients that do not
respond to other medications with severe acne

Take 10-20mg od until all lesions have resolved which is typically 3-5 months then
reduce to half the dose for further months to avoid relapse or scarring

Presentation of cellulitis - Answer Ill defined lesions, red, painful, swollen and may or
may not have systemic symptoms

First line treatment for cellulitis - Answer Flucloxacillin 1g every 6-8 hours for 5 days

For elderly or lower body weight they can take 500mg every 6 hours and 1g every 6
hours for the opposite

High doses are advised to be taken with food to reduce GI disturbances

What strength does flucloxacillin come in - Answer 250mg or 500mg capsules or 250,
500, 1g injections

Why would probenecid be given for patients with cellulitis - Answer If a patient has a
creatinine clearance of <30mL/min then they are given probenecid because it reduces

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