NR 566 week 4 Questions
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treatment of obesity: evaluation of phentermine/topiramate - ANSWER Schedule IV drug indicated
for chronic weight loss. Phetermine suppresses appetite which topirmate increses satiety. Most
common side efrects are dry mouth, constipation, blurred vision, and numbness tingling.
-serious effects are memory loss, concentration, HTN, tachycardia, hypoglycemia
treatment of obesity: evaluation of phentermine/topiramate contraindications: - ANSWER Glaucoma
or hyperthyroid
-Should not be given with MAOI. Stop MAOI 2 weeks before starting.
-Carbonic anhydrase increases risk for metabolic acidosis
-diuretics that are not K+ sparing increases risk for hyperkalemia
Orlistat (Xenical) - ANSWER - Is prescribed to morbidly obese pts to lose weight. It prevents
absorption of some of the fat in the pts diet.
- The med should be taken 3 times/day within 1 hour of a meal
- Its a lipase inhibitor, not an appetite suppressor.
Orlistat (Xenical) adverse effects: - ANSWER Oily rectal leakage, sharting, fecal urgency, and fatty or
oily stools
-increased defecation and incontinence
-rare: severe liver damage —> itching, vomiting, anoxeria, dark urine, light colored stools
-acute pancreatitis and kidney stones
Orlistat (Xenical) contraindications - ANSWER Malabsorption syndrome and cholestasis
, Lorcaserin (Belviq) - ANSWER weight loss drug
Nalrexone (ReVia) - ANSWER Decrease the ability opioid analgesics to relieve pain
-do not take within 2 weeks of a MAOI
Orlistat (Xenical) drug interactions - ANSWER Levothyroxine- may cause hypothyroidism by
decreasing the absorption of thyroid hormone. If drug is needed take them 4 hrs apart
-cyclosporine- can reduce absorption, give them 2-3 hrs apart
Baseline data: Liraglutide - ANSWER HB A1C, lipids, renal function
Assessment of the one administering the injection
Naltrexone/Bupropion (Contrave) adverse reactions - ANSWER N/v, constipation, HA, dizziness, and
insomnia, increase blood pressure, dry mouth, diarrhea, and discomfort, anxiety, and fatigue, SI
thoughts
Naltrexone/Bupropion (Contrave) black box - ANSWER SI, SI attempts in children, adolescents, and
young adults
Naltrexone/Bupropion (Contrave) contradictions - ANSWER Taking other bupropion
Pts with uncontrolled HTN, seizure disorder, eating disorders such as anorexia or bulimia
-those going through alcohol, barbiturate, or benzodiazepine withdrawal
Lorcaserin adverse effects - ANSWER HA, back pain, decrease lymphocytes and URIs, hypoglycemia
in diabetics
Lorcaserin adverse reactions that are less common - ANSWER Blood dye radios, cognitive
impairment, psychiatric disorders, priapism, HTN, valvular heart disease
Weight loss drugscontraindications for children - ANSWER Not recommended.
- orlistat is not approved for kids under 12
Diethylpropion and phentermine are not for children under 16
Weight loss drugs contradictions: pregnancy - ANSWER Not recommended