Summary
Hart en vaatziekten (HVZ) beknopte samenvatting (inc AGHO-lijst)
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samenvatting van hart en vaatziekten inc AGHO lijst
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Hart en vaatziekten: beknopte samenvattingUniversiteit Leiden
Farmacie
Hart en vaatziekten
2023 -
2024
,Inhoud
Artherosclerose
Innovatieve artherosclerose
Crum
Angina pectoris
Stolling en anti stolling (+ complex (
Perifeer vaattijden
Hartfalen
Anemie
Hartritmestoornis
metabolisme : nieu
metabolisme : Lever
metabolisme en eliminatie v .
gom
AGHO-lijst
, ATHEROSCLEROSE
monot u endotheel cl
↓
MCP1 endothelic
↓
B
macrofaag
7
(D((
S
*
(D( *
*
2
G ↳
V
((x
schwimcellen
(DIDL
LDL gaat door het endotheel en kont in het adothelia Cintimal
↳ Door
blootstelling aan diverse Stoffen wordt dit een
gemodificeerde (DC (LDE)
4) Deze
produceert MCP1 Cookwel (112)
↳s stimuleert aantrekking
monocyten
Monocyten *
Komen de cel in
en worden macrofagen
↳ LDI worden
opgenomen en afgebroken tot Vesicles door de
macrofaag
↳
Dit wordt een
macrofag foamce t
worming plaque
Sommige Foamcellen ondergaan apoptose
↳
proliferatie gladde spiercellen
↳ Kapsel om de
plaque heer
Laatste stadium heb
je opstapeling Ca
↳ Calcificatie
Bij een rupture kont het andotheel in contact met het bloed
↳ Start primaire hemostase
↳ Trombus
, I
Lever
ucose- glycerolmonoglycera
:
V
G triglycerd
F
·
empty HDL
↓
S
pyrivate ·
vLDL
Spyrivate
Fatty acids
↓
acetyl-coa
1
Apoprotein Mreagda
eliminatie
-
↓ via gal
>
mono lynal-
acetyl-coa
HMG
Coa
LDL - HDC
2 reductase
i
M
M
Cholestera
D (D
receptor
Bloed
~ V
VLDL empty HDL
> IDL > (D)
Lipase
HDL
1
LDL distribueert cholesterd
: naar weersel
misme
HDL :
Distribueert overtollig Cholesterd terug tissue
neenodig
naar de lever
Elk (DL heeft 1 APO-B
↳ !
APO-B zit niet op HDL
Firewald
Formule : (DL = totalecholes -
HDL -
(0 .
45
xtriglyceride)
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