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PHCY 503 Final Exam Study Guide
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PHCY 503 Final ExamStudy Guide
Aspirin - Answer drug brand name: N/A
drug class: anti-platelet agent, salicylate; NSAID
FDA-approved indications: secondary prevention after acute coronary syndrome
drug target: COX-1
pharmacological role: irreversible, competitive inhibitor
Epinephrine - Answer drug brand name: Adrenalin
drug class: sympathomimetic agent
FDA-approved indications: anaphylaxis
drug target: adrenergic receptors
pharmacological role: agonist
Ibuprofen - Answer drug brand name: Advil, Motrin
drug class: NSAID, analgesic, non-opioid
FDA-approved indications: pain
drug target: COX-1 and COX-2
pharmacological role: reversible competitive inhibitor
Diclofenac - Answer drug brand name: Voltaren
drug class: NSAID, analgesic, non-opioid
FDA-approved indications: pain
drug target: COX-1 and COX-2
pharmacological role: reversible competitive inhibitor
Meloxicam - Answer drug brand name: Mobic
drug class: NSAID, analgesic, non-opioid
,FDA-approved indications: pain
drug target: COX-1 and COX-2
pharmacological role: reversible competitive inhibitor
Naproxen - Answer drug brand name: Aleve
drug class: NSAID, analgesic, non-opioid
FDA-approved indications: pain
drug target: COX-1 and COX-2
pharmacological role: reversible competitive inhibitor
Celecoxib - Answer drug brand name: Celebrex
drug class: NSAID; COX-2 selective; analgesic, non-opioid
FDA-approved indications: pain
drug target: COX-2
pharmacological role: reversible competitive inhibitor
Acetaminophen - Answer drug brand name: Tylenol
drug class: analgesic; non-opioid
FDA-approved indications: pain, fever
drug target: COX-1, COX-2 and COX-3
pharmacological role: reversible competitive inhibitor
Methylprednisolone - Answer drug brand name: Medrol, Solu-Medrol, Depo-Medrol
drug class: corticosteroid, systemic
FDA-approved indications: inflammatory disorders
drug target: glucocorticoid receptor
pharmacological role: agonist
Prednisone - Answer drug brand name: Deltasone, Prednisone Intensol
drug class: corticosteroid, systemic
FDA-approved indications: inflammatory disorders
drug target: glucocorticoid receptor
,pharmacological role: agonist
Cetirizine - Answer drug brand name: Zyrtec
drug class: second generation antihistamine (H1R antagonist)
FDA-approved indications: histamine-mediated allergy symptoms
drug target: H1R
pharmacological role: reversible, orthosteric antagonist
Loratidine - Answer drug brand name: Claritin
drug class: second generation antihistamine (H1R antagonist)
FDA-approved indications: histamine-mediated allergy symptoms
drug target: H1R
pharmacological role: reversible, orthosteric antagonist
Diphenhydramine - Answer drug brand name: Benadryl
drug class: first generation antihistamine (H1R antagonist)
FDA-approved indications: histamine-mediated allergy symptoms
drug target: H1R
pharmacological role: reversible, orthosteric antagonist
Fexofenadine - Answer drug brand name: Allegra
drug class: second generation antihistamine (H1R antagonist)
FDA-approved indications: histamine mediated allergy symptoms
drug target: H1R
pharmacological role: reversible, orthosteric antagonist
Montelukast - Answer drug brand name: Singulair
drug class: leukotriene receptor antagonist
FDA-approved indications: allergic rhinitis, asthma
drug target: CysLT1R
pharmacological role: reversible, orthosteric antagonist
Saquinavir - Answer drug brand name: Invirase
, drug class: antiretroviral, protease inhibitor (anti-HIV)
FDA-approved indications: HIV
drug target: HIV protease
pharmacological role: reversible orthosteric inhibitor
Simeprevir - Answer drug brand name: Olysio
drug class: NS3/4A protease inhibitor; antihepaciviral
FDA-approved indications: chronic hepatitis C with or without cirrhosis
drug target: NS3/4A protease
pharmacological role: competitive reversible inhibitor
Sofosbuvir - Answer drug brand name: Solvadi
drug class: NS5B RNA polymerase inhibitor; antihepaciviral
FDA-approved indications: chronic hepatitis C with or without cirrhosis
drug target: NS5B RNA polymerase
pharmacological role: reversible competitive inhibitor
Amoxicillin - Answer drug brand name: Moxatag, Amoxil
drug class: beta-lactam
FDA-approved indications: bacterial upper respiratory infections
drug target: transpeptidase
pharmacological role: irreversible, competitive inhibitor
Penicillin V Potassium - Answer drug brand name: N/A
drug class: beta-lactam
FDA-approved indications: bacterial upper respiratory infections
drug target: transpeptidase
pharmacological role: irreversible, competitive inhibitor
Cephalexin - Answer drug brand name: Keflex
drug class: antibiotic, first generation cephalosporin
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