Exam (elaborations)
HEMATOPOIETIC SYSTEM EXAM STUDY SET
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HEMATOPOIETIC SYSTEM EXAM STUDY SET2024-2025
major component of RBC - ANSWER B12, folic acid, and iron
life span is only about 120days
erythropoietin - ANSWER made in the kidneys
blood loss equals - ANSWER iron deficiency
normal WBC count - ANSWER about 4,000 - 10,000
leukocytes - ANSWER average lifespan 4-5 days and 6-8hr after activation
made in bone marrow & lymphoid tissue
platelets - ANSWER problems cause bleeding, coagulation, & DIC
2/3 in circulation and the rest are on reserve in the spleen
live 6-10 days
give to stop bleeding or when low
normal platelet count - ANSWER 150,000 - 450,000
normal haemoglobin - ANSWER 11-17 don't need to know the difference between
M/F except that males are a little higher than women
normal hematocrit - ANSWER 38-49 - higher in men than women
normal red blood cell count - ANSWER 4.2-5.14
reticulocyte - ANSWER baby RBC
should expect an increase after giving iron to ensure RBCs are being made
normal MCV - ANSWER size of RBC
,85-95(fl)
normal MCHC - ANSWER 33-35g/dL
normal PTT - ANSWER 25-39sec
normal PT - ANSWER 10-13sec
normal INR - ANSWER <2
on coumadin: 2-3
peripheral blood smear - ANSWER determination of the morphology of the cells,
the extent of cell maturity and the ratio of the various
can see sickling of cell in sickle cell anaemia crisis
bone marrow aspiration - ANSWER bone marrow sample examined when
diagnosis is not clearly determined by the PBS
shilling test - ANSWER checking for B12 deficiency only
Coombs test - ANSWER looking for antibodies (blood transfusion reaction)
Epogen - ANSWER epoetin alpha
erythropoietin that normally comes from the kidney
stimulates RBC production
B12 - ANSWER cyanocobalamin
folic acid - ANSWER folate
iron - ANSWER ferrous sulfate
vitamin K - ANSWER phytonadione
neupogen - ANSWER filgrastim
stimulates the production of WBC
whole blood - ANSWER when a person needs all the components of the blood plus
volume
, PRBC (packed red blood cells) - ANSWER given when we don't need the volume
FFP (fresh frozen plasma) - ANSWER gives us volume and clotting factors
cryoprecipitate - ANSWER take liquid off plasma and you have a precipitate - just
gives the clotting factors
2 reasons one can bleed - ANSWER deficiency in platelets
deficiency in clotting factors
anemia s/sx - ANSWER low Hgb/Hct
fatigue
skin, conjuctiva are pale
HR is increased
exertional dyspnea
macrocytic - ANSWER RBC is large; >95 MCV
microcytic - ANSWER RBC is small; <85 MCV
"chromic" - ANSWER hemoglobin content
"cytic" - ANSWER cell size
macrocytic - normochromic anemia - ANSWER big cell, normal amount of
hemoglobin anemia
elevated MCV, & normal MCHC
ex: pernicious anemia, Vit. B12 deficiency, folic acid deficiency
pernicious anemia - ANSWER macrocytic normochronic anemia
increased MCV, & normal MCHC
have B12 but can't absorb because of no intrinsic factor
so ends up with B12 deficiency
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