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Katholieke Universiteit Leuven (KU Leuven)
Bio Ingenieurswetenschappen
Advanced Genetics (I0I19A)
Summary
Summary Table of Contents for Advanced Genetics (accompanying the purchased course text)
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Course
Advanced Genetics (I0I19A)
Institution
Katholieke Universiteit Leuven (KU Leuven)
Table of Contents for the Advanced Genetics course.
This is provided in a separate document, so the sample pages from the course text clearly showcase my notes.
Molecular Genetics
MASTER BIOSCIENCE ENGINEERING: CELLULAR AND GENETIC
KIRSTEN VAN GILS
Kirsten Van Gils (2023-2024)
, PART 1: GENETIC VARIATION
CHAPTER 1: STRUCTURE, ORGANIZATION AND REPLICATION OF GENOMES
PART A: EUKARYOTIC GENOMES
1. Structure and replication of the chromosome
1.1. Centromere, telomere, replication
1.2. Three-dimensional structure of the chromosome: packaging of DNA
1.3. Regulation of chromatin structure
1.4. Nucleosome assembly
2. Genes and repetitive sequences in chromosomes
PARTB: BACTERIAL GENOMES
1. replication , cell division and coordination
1.1. replication
1.2. Cell division
1.3. Coordination
1.4. Timing of initiation of chromosome replication
1.5. Comparison organization and regulation of DNA replication –segregation conflict replication/transcription of
chromosomes in eukaryotes and bacteria
2. structure, physical properties
2.1. structure
2.2. Physical properties
CHAPTER 2: GENE MUTATION AND REPAIR
INTRODUCTION: GENE MUTATION
REPLICATION ERRORS AND REPAIR OF REPLICATION ERROS
1. Replication errors
2. repair of replication errors
DNA DAMAGE
1. hydrolysis
2. alkylation, oxidation and radiation
3. base analogues and intercalating agents
REPAIR AND TOLERANCE OF DNA DAMAGE
1. direct repair of DNA damage
2. base excision repair
3. nucleotide excision repair
4. repair of double-stranded breaks
5. translesion DNA synthesis
6. suppression of mutations
Kirsten Van Gils (2023-2024)
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