WGU D027 Advanced Pathopharmacological
Foundations Latest Update 2024-2025 Questions and
100% Verified Correct Answers Study Guide
1. What is Celiac Disease and which testing?
• Lining of the small intestine: intolerant of gluten
• Testing for Celiac Disease is IgA-tTG, Total IgA
2. What is Sjogrens Syndrome and which testing?
• Mostly in older women but can occur any age & affects primarily those with Rheumatoid
arthritis or SLE
• Immune system disorder characterized by dry eyes and dry mouth
• Testing for Syndrome are SSA + & SSB+
4. Hypoplastic Left Heart Syndrome (HLHS), what is affected?
• Is a birth defect that affects normal blood flow through the heart.
• Congenital heart defects-mean present at birth
three- to five-year survival rates of 70% for infants who have the stage I repair.
For children who survive to the age of 12 months, long-term survival is about
90 percent.
Dx with echocardiogram Tx Surgical Procedure
S/SX:
rapid breathing or shortness of breath
rapid heartbeat or pounding heart
poor suckling and feeding
cold extremities (poor perfusion)
blue color of the skin, lips and nailbeds (cyanosis)
weakness
• Heart Structure on Left side do not fully develop: Involved
Left ventricle-not formed or too small
Mitral valve- not formed or very small
Hypoplastic Aortic valve is not formed or very small
Ascending portion of the aorta is undeveloped or is too small
Atrial septal defect-whole is a hole between the left and right upper chambers (atria) of
the heart
, • There are two small openings between the left and right sides of the heart: the patent ductus
arteriosus and the patent foramen ovale. During the first few days of life for a baby with
hypoplastic left heart syndrome, the oxygen-rich blood bypasses the poorly functioning left side
of the heart through the patent ductus arteriosus and the patent foramen ovale.
5. What does Parathyroid secretes?
Calcium (Ca+)
6. What is Hutchinson-Gilford Progeria Syndrome?
• Progressive genetic disorder cause children to age rapidly. No cure
• Caused by aberrant splicing of the LMNA making protein-progerin
• Age 10x faster s/sx:
short stature or slow growth
slow hair growth
hair loss
first 2yrs of life tooth delayed
wrinkle/dryness skin
Treatment: NSAID Statin; Bone Health
7. What Medicine is used for Diabetic neuropathy pain?
The best medicine used is Cymbalta, Lyrica (Pregabalin)
8. Hydrotherapy helps with what disease?
Hydrotherapy helps with Multiple Sclerosis (MS) or Myasthenia Gravis (MG)
9. Patient with Post MVA, had right side decreased lung sounds?
Pneumothorax when air leak into space between the lungs and chest wall d/t blunt or
penetrating chest injury
10. Which TB med impacts oral contraceptives?
Rifampin-oral contraceptives cannot be relied upon for birth control while taking this
antibiotics
11. What are TSH/T4/T3 abnormal levels for hypothyroidism
TSH-normal level.4 to 4.0 milli-international unit per liter, if you are being treated .5 to
4.0
High TSH levels mean thyroid is not making enough thyroid hormoneshypothyroidism
Low TSH levels mean thyroid is making too much of the hormones- hyperthyroidism
T4-normal level 5.0 to 12 ug/dl elevated level indicates hyperthyroidism; elevated
indicate hyperthyroidism
Also, low level, can indicate thyroiditis or toxic multinodular goiter
T3-normal level 80-220ng/dl low level indicates hypothyroidism or starvation. Elevated
indicates hyperthyroidism
Long term illness can cause T3 to be low
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