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Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), Chapter 1-61 | All Chapters$17.49
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1. Ahwomanhdiagnosedhwithhobsessive–
compulsivehdisorderhhashbeenhprescribedhoralhparoxetinehhydrochl
oride.hWhathishthehexpectedheffecthforhthishprescription?
A. Curativeheffecthonhsymptoms
B. Systemicheffecthonhsymptoms
C. Localheffecthonhsymptoms
D. Parenteralheffecthonhsymptoms
ANS:h B
Rationale:hDrugshthathproducehsystemicheffectsharehtakenhintohthehbo
dy,hcirculatedhthroughhthehbloodstreamhtohtheirhsiteshofhactionhinhvari
oushbodyhtissues,handheventuallyheliminatedhfromhthehbody.
Curativehagentsharehgivenhtohcurehahdiseasehprocess.hInhthishcase,hpar
oxetinehhydrochloridehwillhcontrolhthehsymptomshbuthnothcurehthehdis
order.hDrugshwithhlocalheffects,hsuchhashsunscreenhandhlocal
anesthetics,hacthmainlyhaththehsitehofhapplication.hParoxetinehhydrochloridehishnothadministeredhpar
enterally.hParenteralhagentsharehadministeredhsubcutaneously,hintramuscularly,horhintravenously.
A. Synthetichdrug
B. Semisynthetichdrug
C. Biotechnologyhdrug
D. Prototypehdrug
ANS:h B
Rationale:hSemisynthetichdrugsh(e.g.,hmanyhantibiotics)harehnaturallyhoccurringhsubstanceshthathha
vehbeenhchemicallyhmodified.hSynthetichdrugsharehmorehstandardizedhinhtheirhchemicalhcharacteris
tics,hmorehconsistenthinhtheirheffects,handhlesshlikelyhtohproducehallergichreactions.
BiotechnologyhdrugshinvolvehmanipulatinghDNAhandhRNAhandhrecombininghgeneshintohhybridhm
oleculeshthathcanhbehinsertedhintohlivinghorganisms.hPrototypehdrugsharehthehfirsthdrughofhahparticul
arhgrouphtohbehdeveloped.
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