WWW.THENURSINGMASTERY.COM Page 1 of 247 Test Bank to accompany Psychopharmacology, Third Edition Meyer • Quenzer Chapter 1: Principles of Pharmacology Multiple Choice 1. refer(s) to specific molecular changes that occur when a drug binds to a particular target site or receptor, while are the resu...
Test hBank
to haccompany
Psychopharmacology, hThird hEdition
Meyer h• hQuenzer
Chapter h1: hPrinciples hof hPharmacology
Multiple hChoice
1. h refer(s) hto hspecific hmolecular hchanges hthat hoccur hwhen ha hdrug hbinds
hto ha hparticular htarget hsite hor hreceptor, hwhile are hthe hresulting hwidespread
halterationshin hfunction.
a. Drug haction; htherapeutic heffects
b. Side heffects; hdrug heffects
c. Therapeutic heffects; hside heffects
d. Drug haction; hdrug heffects
Answer: hd
Textbook hReference: hPharmacology: hThe hScience hof hDrug hAction
2. After hdrug hadministration hhas hoccurred, hthe hamount hof hdrug hin hthe hblood hthat
his hfree htohbind hat hspecific htarget hsites his hreferred hto h as
a. the htherapeutic hdose.
b. first-pass heffects.
c. bioavailability.
d. ED50.
Answer: hc
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
3. The hspecific hmolecular hchanges hthat hoccur hwhen ha hdrug hbinds hto ha hparticular
htarget hsitehor hreceptor hare hreferred hto has
a. drug heffects.
b. drug haction.
c. side heffects.
d. placebo heffects.
Answer: hb
Textbook hReference: hPharmacology: hThe hScience hof hDrug hAction
4. Which hof hthe hfollowing his hnot ha hpossible hexplanation hfor hplacebo heffects?
a. Pavlovian hconditioning
b. Genetic hvariation
c. Drug hcompetition
d. Expectation hof houtcome
Answer: hc
Textbook hReference: hPharmacology: hThe hScience hof hDrug hAction
5. The administration hof hoxytocin hhas hbeen hproposed has ha htreatment hfor
hautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: hc
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
6. Which hfactor hdoes hnot haffect hthe hpharmacokinetics hof ha hdrug?
a. Route hof hadministration
b. Lipid hsolubility
c. Depot hbinding
d. Drug haction
Answer: hd
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
7. First-pass hmetabolism hoccurs hwhen hdrugs hare htaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: ha
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
8. The harea hpostrema his hone harea hin hthe hbrain hwhere hthe is hnot hcomplete.
a. cerebrospinal hfluid
b. blood–brain hbarrier
c. choroid hplexus
d. phospholipid hmembrane
Answer: hb
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
9. First-pass hmetabolism hoccurs hwith horally hadministered hdrugs hbecause
a. their habsorption his hslowed hby hfood.
b. drugs habsorbed hinto hthe hbloodstream hfrom hthe hstomach hgo hto hthe hliver hon
hthe hway htohgeneral hcirculation.
c. drugs hmust hfirst hsurvive hthe hacidic henvironment hof hthe hstomach.
d. salivary henzymes hin hthe hmouth hbegin hthe hprocess hof hmetabolism.
Answer: hb
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
10. Toxic hsubstances hin hthe hblood htrigger ha hvomiting hresponse hby hactivating hthe
a. blood–brain hbarrier.
b. choroid hplexus.
c. area hpostrema.
d. median heminence.
Answer: hc
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
11. Drugs hadministered h_ have hthe hmost hrapid honset hof haction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: hd
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
12. Ionization hof ha hdrug hdepends hon hthe of hthe hsolution hand hthe of
hthehdrug.
a. pH; hpKa
b. pKa; hpH
c. concentration; hlipid hsolubility
d. pH; hconcentration
Answer: ha
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
13. The habsorption hof ha hdrug hdepends hon hall hof hthe hfollowing hexcept
a. lipid hsolubility.
b. ionization.
c. body htemperature.
d. the hconcentration hof hthe hdrug.
Answer: hc
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
14. Drugs hthat hare should hbe havoided hby hwomen hof hchildbearing hage.
a. teratogenic
b. able hto hcross hthe hplacental hbarrier
c. psychoactive
d. highly hlipid-soluble
Answer: ha
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
15. Agents hthat hinduce hdevelopmental habnormalities hin ha hfetus hare hknown has
a. psychoactive hdrugs.
b. illicit hdrugs.
c. teratogens.
d. placental hdrugs.
Answer: hc
Textbook hReference: hPharmacokinetic hFactors hDetermining hDrug hAction
16. Depot hbinding his hsaid hto hoccur hwhen hdrugs
a. bind hto htheir htarget hsites.
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