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CLS306 BLOOD BANK FINAL EXAM (V1) COMPLETE QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS )| (V2) CLS 306 FINAL EXAM REVIEW|COMPLETE QUESTIONS AND CORRECT ANSWERS |ALREADY GRADED A+.$22.49
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CLS306 BLOOD BANK FINAL EXAM (V1) 2024-2025 COMPLETE
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS )| (V2)
CLS 306 FINAL EXAM REVIEW|COMPLETE QUESTIONS AND
CORRECT ANSWERS |ALREADY GRADED A+.
There are 2 alleles that are discovered: allele W and allele w. If W Frequency
is 84% and the w gene frequency is 16%, what is the gene frequency of the
dominant allele W?
0.6 –ANSWER.
There are 2 alleles that are discovered in a new population. There are allele W
and allele w. If W gene frequency is 75% and the w gene frequency is 25%,
what is the gene frequency of the dominant allele W? 0.5 –ANSWER.
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What is the
expression of the ABO genes?
Codominant –ANSWER.
Which of the following must be true when using the Hardy-Weinberg
equation? All of the above –ANSWER.
• The population must be large
• Mutations cannot occur
• Mating must occur randomly
What class of immunoglobulin is capable of crossing the placenta?
IgG –ANSWER.
What is a possible explanation for a weak reaction (1+) in a reverse ABO
grouping test? All of the above -ANSWER
,• Elderly patient
• Immunocompromised patient
• IgM deficiency
At what age do infants begin to produce their own antibodies?
Six months –ANSWER.
Which IgG subclasses are of greatest clinical significance in the Rh Blood
Group System?
IgG1 and IgG3 –ANSWER.
What does hemolysis represent in an antigen-antibody reaction?
A positive result –ANSWER.
At what temperature do IgG antibodies react optimally?
37°C –ANSWER.
In an immune response ________________________ antibodies are formed
before ________________________?
IgM, IgG –ANSWER.
A father is typed as group B, the mother is group A, determine the maximum
theoretical types that the offspring could be:
A, B, AB, O –ANSWER.
What component of the Hardy-Weinberg equation signifies the
heterozygotes?
2pq –ANSWER.
Which of the following criteria is used to classify the B subgroups?
All of the above –ANSWER.
• Agglutination patterns with anti-B, anti-AB, and anti-A
• Presence of ABH agglutinins in the serum
• Absorption-elution studies with anti-B
, What antibodies are found in the serum of a Bombay phenotype?
anti-A, anti-B, anti-A,B, and anti-H –ANSWER.
A type-A person demonstrate a 2+ reactivity with A1 cells (reverse grouping)
and a 4+ reactivity with B cells. The forward grouping with anti-A is 4+ and
anti-B is negative. Therefore, the possibility of a subgroup is excluded. The
antibody screen is weakly positive at 37°C, but shows no reactivity at the
AHG phase. An antibody panel is performed and anti M is identified. The
patient phenotypes negative for M antigen. How is the ABO discrepancy
resolved?
Perform reverse grouping with A1 cells negative for M antigen. –
ANSWER.
Which of the following is not characteristic of antibodies within the ABO
system?
ABO antibodies do not activate complement. –ANSWER.
What ABO group contains the least amount of H substance?
A1B –ANSWER.
The genotypes of an AB male mates with an AB female. What could be the
phenotype of the offspring? All of the above –ANSWER.
• AB
•A
•B
What immunodominance sugar is responsible for O specificity?
L-fucose
G-antigen is present on all of which type of red blood cells?
DC-positive
Which antigen represents Rh3 in Rosenfield terminology?
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