Applied pathophysiology for the advanced practice nurse 1st edition dlugasch story test bank
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Instructor Resource Guide for Applied Pathophysiology for
the Advanced Practice Nurse, Second Edition by Lucie
Dlugasch 2024 A+
Chapter 1: Cellular Function
Chapter Objectives • Analyze the purpose and function of cellular structures.
• Analyze how various substances cross the cell membrane.
• Explain cellular energy sources and production.
• Discuss the process of protein synthesis.
• Summarize how cells are organized.
• Analyze mechanisms of cellular proliferation, differentiation, and adaptation as they
relate to disease development.
• Describe the correlation between genetics, epigenetics, and environment in disease
development.
• Evaluate patterns of inheritance and compare how various disorders are inherited.
• Compare and contrast genetic and congenital disorders.
Chapter Highlights This chapter discusses essential knowledge of basic cellular function and
dysfunction.
Learning Activities and Resources
Online Interactive Lectures The interactive lectures can be used as a self-paced, stand- alone
online course, or they can be assigned to students as part of a blended classroom approach.
As part of a blended approach (e.g., a flipped classroom approach) the interactive lectures
introduce students to the content that will be further discussed during class.
• Instruct students to complete the online interactive lectures and answer the Stop and
Think exercises within each chapter before the next class meeting.
• Although the student can complete the chapter in one sitting, if he or she needs to take a
break, recommend that they pause after a Stop and Think activity.
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Textbook Chapters The online interactive lectures focus on core foundational knowledge.
Each textbook chapter includes Diagnostic Links, Learning Points, Emerging Research, and
Application to Practice boxed features; tables; and figures not included in the interactive lectures.
In addition, you may want to refer your students to the textbook for more detailed discussions of
the following:
• Cell structure (see Cellular Components and Table 1-1)
• Cellular permeability (see Exchanging Material and Figure 1-2, 1-3, 1-4, and 1-5)
• Cell energy production (see Energy Production)
• Genetic information in the cell (see Chromosomes, DNA, and Genes)
• Cell cycle (see Replication and Differentiation)
• Types of genomic mutations (see Genomic Instability)
• Selected Cancer Screening Guidelines (see Table 1-5)
• Prenatal Genetic Disorder Testing (Table 1-7)
Practice Activities Multiple choice study questions are provided for students to assess their
understanding of the content. Students receive immediate feedback about their answer selection,
allowing for deeper understanding. These questions are not graded.
Case Studies Each case study provides a real-world context for students to see what they have
learned put into action.
Discussion Question: Graded The discussion question is available online and included below as
well.
Have students respond to the question on the online discussion forum or use it in the classroom
to guide an in-class discussion.
Online discussion forum:
The textbook provides an extensive overview of cellular structures and their functions. Choose a
specific topic discussed in the text (e.g., cellular components, cellular permeability, energy
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production, or cellular replication and differentiation) and explain why it is important for a nurse
to understand this topic.
Provide an example from your practice where you have used your knowledge of basic cellular
function when interacting with patients. After your original post, you are expected to provide a
meaningful response to at least two other students.
In-class discussion:
Why is it important for a nurse to understand the specifics of cellular function? What are some
real-world examples of using this information in practice?
Answer: Answers will vary, but students should first discuss their beliefs regarding the
importance of understanding cellular function and then relate a basic cellular concept directly to
practice. A nurse may focus on how knowledge of cellular replication and differentiation
(including DNA, chromosomes, and genes) can help explain the value of genetic testing to
patients hoping to conceive.
For example, a nurse may have discussed heritability of sickle cell anemia with two patients with
sickle cell trait.
This could include explanations of genotypes versus phenotypes, meiosis, chromosome
inheritance, and the difference between dominant and recessive genes. The student would ideally
provide an example of how this patient education improved patient outcomes.
Grading: Discussion questions should be graded according to your institution’s rubric for online
discussion posting.
Assignment: Graded The following assignment is available online as well. Students can
complete the assignment through the online course, or this can be assigned outside of the online
course.
Assignment:
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Choose one of the types of cancer listed in Table 1-5. Write a research paper that describes
typical pathogenesis, screening guidelines, risk factors, and treatment strategies for this disease,
with a specific focus on how they relate to the cellular function topics discussed in the chapter.
Submit your 2- to 4-page paper, in APA style, by the due date.
Answer: Answers will vary. Students should clearly identify the condition and then touch on all
of the specifics mentioned in the prompt. For example, a student may choose cervical cancer.
That student should discuss typical pathogenesis (i.e., association with human papillomavirus),
screening guidelines (i.e., cytology every 3 years from ages 21 to 65), risk factors (i.e., history of
precancer or cancer within 20 years), and treatment strategies (e.g., surgical removal of lesions).
Recent research and professional experiences should be highlighted. Students should be sure to
relate the disease process and treatment to cellular function.
Grading: Assignments should be graded according to your institution’s rubric for written
assignments.
Chapter Quizzes: Graded Chapter quizzes are available online.
Grading: Chapter quizzes report to the gradebook. Multiple choice and true/false questions will
be automatically graded. Short-answer questions will need to be manually graded.
PowerPoint lecture slides A slide deck of lecture slides is available. These provide an
overview of talking points and are especially useful for lecture presentations.
Chapter 2: Immunity
Chapter Objectives • Explain the role of the body’s normal defenses in preventing
disease.
• Describe the similarities and differences between innate and adaptive immunity.
• Differentiate between infectious disorders.
• Discuss the various types of vaccines and their use in different clinical scenarios.
• Compare and contrast the pathogenesis of hypersensitivity by mechanism and antigen.
• Apply understanding of altered immune responses when describing and discussing
common disorders such as systemic lupus erythematosus and human immunodeficiency virus
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