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TEST BANK FOR JULIEN'S PRIMER OF DRUG ACTION 15TH EDITION BY ROBERT JULIEN, CLAIRE ADVOKAT, JOSEPH COMATY (ALL CHAPTERS, 100% ORIGINAL VERIFIED, A+ GRADE) EXAM QUESTIONS AND100% CORRECT COMPLETE ANSWERS WITH RATIONALES WELL EXPLAINED AND VERIFIED BY EX$24.04
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TEST BANK FOR JULIEN'S PRIMER OF DRUG ACTION 15TH EDITION BY ROBERT JULIEN, CLAIRE ADVOKAT, JOSEPH COMATY (ALL CHAPTERS, 100% ORIGINAL VERIFIED, A+ GRADE) EXAM QUESTIONS AND100% CORRECT COMPLETE ANSWERS WITH RATIONALES WELL EXPLAINED AND VERIFIED BY EX
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JULIEN\'S PRIMER OF DRUG ACTION
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JULIEN\'S PRIMER OF DRUG ACTION
TEST BANK FOR JULIEN'S PRIMER OF DRUG ACTION 15TH EDITION BY ROBERT JULIEN, CLAIRE ADVOKAT, JOSEPH COMATY (ALL CHAPTERS, 100% ORIGINAL VERIFIED, A+ GRADE) EXAM QUESTIONS AND100% CORRECT COMPLETE ANSWERS WITH RATIONALES WELL EXPLAINED AND VERIFIED BY EXPERTS AND GRADED A+ WITH PROOF ALREADY PASSED!!...
TEST BANK FOR JULIEN'S PRIMER OF
DRUG ACTION 15TH EDITION BY
ROBERT JULIEN, CLAIRE ADVOKAT,
JOSEPH COMATY (ALL CHAPTERS, 100%
ORIGINAL VERIFIED, A+ GRADE) EXAM
QUESTIONS AND100% CORRECT
COMPLETE ANSWERS WITH
RATIONALES WELL EXPLAINED AND
VERIFIED BY EXPERTS AND GRADED A+
WITH PROOF ALREADY PASSED!!!!!!!!!
WITH 100% GUARANTEED SUCCESS
AFTER DOWNLOAD (ALL YOU NEED TO
PASS YOUR EXAMS)
,
, What are some concerns of first-pass metabolism? Drugs that are sensitive and heavily
metabolized when exposed to these are usually not given orally. IV would skip the metabolism through
gut lumen and liver to deliver the drug directly to the bloodstream.
Name and give the volumes of three pharmacokinetic water compartments found in the body. Plasma
4L
Interstitial volume 10L
Intracellular volume 28L
Barriers separating plasma and interstitial compartments diffusion across capillary endothelial
cell membrane or between the cells
Barrier between interstitial and intracellular compartments diffusion across membranes
List the factors that influence water-soluble drug distribution between compartments 1) drug size and
lipophilic character
2) tissue quality (capillary permeability, size, and blood flow)
C0= plasma concentration at time zero
Vd= he apparent volume of distribution. The theoretical volume required to make the drug
concentration throughout the body the same as it is in the plama. It lets you calculate the drug dose
needed to achieve a desired plasma concentration.
Major drug metabolizing organ liver
how the body processes a drug (where does it go and how does it get rid of it) pharmacokinetics
Name the 4 important aspects of pharmacokinetics Absorption
Distribution
Metabolism
Elimination
Route of drug administration: oral; convenient but slow delivery and has to go through GI tract Enteral
Route of drug admin: IV, IM, SC; for immediate action but irreversible and skilled personnel required
Parenteral
Route of drug administration: sublingual, inhalation, rectal; rapid delivery, convenient but there are few
drugs available via this manner Mucous membrane
Route of drug admin: topical; simple, convenient but slower delivery and requires a highly lipophilic drug
Transdermal
What are some factors that influence the choice of drug administration? (5) drug properties
site of action
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