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Huether and McCance's Understanding Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean $17.99   Add to cart

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Huether and McCance's Understanding Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean

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Huether and McCance's Understanding Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean

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  • September 10, 2024
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  • 2024/2025
  • Exam (elaborations)
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TEST BANK For Huether and McCance's Understanding
Pathophysiology, Canadian 2nd Edition by Kelly Power-Kean
When does a person experience stress? - ANSWER:When a demand exceeds a
person's coping abilities

What did Dr. Hans Selye do? - ANSWER:Worked to discover a new sex hormone by
injecting ovarian extracts into rats and witness structural changes. He referred to
these stimuli as "stressors"

What are the stages of general adaptation syndrome (GAS) - ANSWER:1. Alarm
2. Resistance/adaptation
3. Exhaustion (allostatic overload)

What happens during the alarm stage of GAS? - ANSWER:Stressor triggers the
hypothalamic-pituitary-adrenal (HPA) axis

Activates sympathetic nervous system

Arousal of body defenses

What happens during the resistance/adaptation stage of GAS? - ANSWER:Begins
with the actions of adrenal hormones

Mobilization contributes to fight or flight

What happens during the exhaustion stage (allostatic overload) of GAS? -
ANSWER:Occurs only if stress continues and adaptation is not successful

Leads to stress-related disorders

Map the sequence of events during the alarm stage - ANSWER:HPA axis stimulates
cortisol release which causes gluconeogensis, glycolysis, lipolysis and protein
catabolism which leads to increased glucose levels and increases the amount of
available ATP

The HPA axis also stimulates epinephrine release which causes and increased heart
rate, breathing rate and blood sugar

Which psychological factors are necessary for the GAS response? - ANSWER:Reactive
response
Anticipatory response
Conditional response

, What is the definition of stressor/coping - ANSWER:Stress begins with a stimulus that
the brain perceives as stressful and in turn promotes adaptation and survival-related
physiologic responses

Distinguish the anticipatory from the reactive response - ANSWER:Anticipatory
response: you have trauma in the past (PSTD)
Occurs when body mounts a physiologic response in anticipation of disruption of
homeostasis

Reactive Response: after the stress
Physiological response derived from psychological stressors

How does the HPA axis affect the nervous system during stress? -
ANSWER:Hypothalamus secretes corticotropin-releasing hormone (CRH)

Pituitary releases adrenocorticotropin hormone (ACTH)

How does the HPA axis affect the endocrine system during stress? -
ANSWER:Adrenals secrete cortisol and catecholamines

How does the HPA axis affect the immune system during stress? - ANSWER:Multiple
alterations secondary to cortisol and catecholamines

decreases T cell cytotoxicity and B cell function which decreases antibody production

Immunosuppression or enhanced humoral immunity

Anti-inflammatory or pro-inflammatory

Cortisol and catecholamines decrease cellular immunity while increase humoral
immunity and acute inflammation

What coordinates neuroendocrine regulation? - ANSWER:The hypothalamus

Psychoneuroimmunology (PNI - ANSWER:how the brain/spinal cord work together
with the body's defenses work against external infection and abnormal cell division

Psycho (CNS)
Consciousness
Endocrine
Brain and spinal cord
Immune
Immune modulation by psychosocial stressors leads directly to health outcomes

Is reproduction and growth stimulated or suppressed during stress? -
ANSWER:Suppressed

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