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Introductory Clinical Pharmacology, 12th Edition By Susan Ford
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Introductory Clinical Pharmacology, 12th Edition By Susan Ford
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TEST BANK FOR INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION BY FORD ALL CHAPTERS INCLUDED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+|| ASSURED PASS!!!
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TEST BANK FOR INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION BY SUSAN FORD CHAPTER 1-54 | COMPLETE GUIDE
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TEST BANK For Introductory Clinical Pharmacology, 12th Edition By Susan Ford, Verified Chapters 1 - 54, Complete Newest Version
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TEST BANK For Introductory Clinical Pharmacology, 12thEdition By Susan Ford
What are sources of drugs? - ANSWER:- plants
- animals
- chemical synthesis
What is pharmacogenetics? - ANSWER:the effect of a single gene on drug response
What is pharmacogenomics? - ANSWER:the effects of many genes on a patient's
response to treatment
Pharmacogenomics is most beneficial for medications with... - ANSWER:- high
interpersonal variability
- narrow therapeutic index
- nonlinear pharmacokinetics
What are pharmacokinetic variations? - ANSWER:genotypic inheritance patterns of
cytochrome P450 genes may alter metabolism of certain medications
What are pharmacodynamic variations? - ANSWER:genetic variation of receptors,
signaling proteins
How many base pairs are in the human genome? - ANSWER:3 million
What percentage of DNA is identical between any 2 people? - ANSWER:99.6%
How many base pairs represent genetic variability? - ANSWER:12 million
What is the "wild type"? - ANSWER:normal most frequently occurring genotype
What is a genotype? - ANSWER:gene pattern
What is a phenotype? - ANSWER:the presentation of the gene
What was the purpose of the Genetic Information Non-Discrimination Act of 2008? -
ANSWER:protects patients from discrimination on the basis of genetic information in
both health insurance and employment
What are the components of the dose response curve? - ANSWER:- ceiling effect
- potency
- duration of action
- onset of action
What are the FDA requirements for drug approval? - ANSWER:safe and effective
, What does ED50 stand for? - ANSWER:effective dose 50
What does LD50 stand for? - ANSWER:lethal dose 50
How is the therapeutic index calculated? - ANSWER:TI = LD50/ED50
What was the first drug law that requires drugs to have a minimal strength and
purity? - ANSWER:1906 - Federal Pure Food and Drug Act
Why was the Federal Pure Food and Drug Act put into place? - ANSWER:Swill milk
In what year was an amendment made to the 1906 law? - ANSWER:1912
What did the amendment to the 1906 law include? - ANSWER:included regulations
for labeling and false claims of effectiveness
What was the 1938 law that gave authority to the FDA? - ANSWER:Federal Food and
Cosmetic Act
What did the Federal Food and Cosmetic Act do? - ANSWER:it set safety standards
and looked for toxicity
Why was the Federal Food and Cosmetic Act put into place? - ANSWER:sulfanilamide
elixir disaster of 1937 (powdered sulfanilamide mixed with diethylene glycol killed
100 people)
What was the name of the 1962 amendment to the 1938 law? - ANSWER:Kefauver-
Harris Amendment
What did the Kefauver-Harris Amendment do? - ANSWER:- required animal testing
to be done prior to human testing
- established clinical requirements for human drug testing
What was the 1970 drug legislation act? - ANSWER:Federal Comprehensive Drug
Abuse Prevention and Control Act
What was the purpose of the Federal Comprehensive Drug Abuse Prevention and
Control Act? - ANSWER:- "Controlled Substance Act"
- regulates the dispensing of "controlled" substances that have the potential for
abuse
Schedule 1-5
What was the drug legislation act of 2007? - ANSWER:Food and Drug Administration
Amendments Act (FDAA)
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