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NR 507 WEEK 4-8 QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

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  • Course
  • NR 507 Advanced Pathophysiology
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  • NR 507 Advanced Pathophysiology

NR 507 WEEK 4-8 QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

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  • September 10, 2024
  • 90
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 507 Advanced Pathophysiology
  • NR 507 Advanced Pathophysiology
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NR 507 WEEK 4-8 QUESTIONS AND
ANSWERS WITH SOLUTIONS 2024
LowerKUrinaryKTractKInfections

AKsymptomKofKaKlowerKurinaryKtractKinfectionKincludes:

A.KFever

B.KUrgency

C.KFlankKpain

D.KDecreasedKUrinationK-KANSWERKUrgencyKisKaKsymptomKofKlowerKtractKUTI..



UrinaryKTractKInfection

WhichKofKtheKfollowingKisKaKriskKfactorKforKtheKdevelopmentKofKaKurinaryKtractKinfectionK(UTI)?

A.KPerimenopause

B.KFrequentKshowering

C.KPregnancy

D.KMarathonKrunningK-KANSWERKPregnancyKisKaKriskKfactorKtheKdevelopmentKofKaKUTI.



ComplicatedKUrinaryKTractKInfections

WhichKofKtheKfollowingKisKtrueKregardingKaKcomplicatedKurinaryKtractKinfection?

A.KCanKbeKcausedKbyKaKstructuralKurinaryKtractKdisorder

B.KItKisKusuallyKasymptomatic

C.KIsKassociatedKwithKyoungKadults

D.KBacteriaKisKlocatedKmostlyKinKtheKlowerKurinaryKtractK-
KANSWERKAKcomplicatedKUTIKcanKbeKcausedKbyKaKstructuralKissueKinKtheKurinaryKtract.




UrinaryKTractKInfections

WomenKareKatKaKhigherKriskKforKtheKdevelopmentKofKaKUTIKbecauseKofKhavingKaKshorterKurethra.

True

FalseK-KANSWERKTrue:KWomenKhaveKaKshorterKurethraKthatKputsKthemKatKhigherKriskKforKdevelopingKaKUTI.

,PreventingKUTIs

WhichKofKtheKfollowingKcanKhelpKtoKpreventKaKUTI?

A.KUseKspermicidesKduringKsexualKintercourse

B.KTakingKmoreKVitaminKD

C.KDouchingKtoKpreventKtheKgrowthKofKbacteria

D.KIncreaseKwaterKconsumptionK-
KANSWERKIncreaseKwaterKconsumption.KWaterKconsumptionKpreventsKUTIKasKitKkeepsKbacteriaKflushedKout

KofKtheKurinaryKtract.




UrinaryKTractKInfections

UrinaryKtractKinfectionsK(UTI)KareKcommonlyKseenKinKclinicalKpractice.KBacteriaKfromKtheKgutKcanKinvadeKth
eKurinaryKepitheliumKtoKcauseKinflammationKandKinfectionKanywhereKalongKtheKurinaryKtractKsuchKasKtheKu
rethra,Kbladder,Kureter,KorKkidney.KSomeKindividualsKareKpredisposedKtoKdevelopingKaKUTI.KItKisKmoreKcomm
onKforKwomenKtoKdevelopKaKUTIKespeciallyKwhenKpregnant,KsexuallyKactive,KduringKpost-
menopauseKwithKestrogen-
deficiencyKandKwhenKbeingKtreatedKwithKantibioticsKwhereKtheKnormalKbacteriaKfloraKisKdiminished.KAlthou
ghKlessKcommon,KmenKmayKdevelopKaKlowerKUTI.KAnKupperKUTIKisKlessKcommonKinKmenKdueKtoKtheKlongerK
urethraKandKureterKstructuresKthatKmakeKitKmoreKdifficultKforKbacteriaKtoKreachKtheKkidney.KAnKindwellingKu
rinaryKcatheterKcanKalsoKcontributeKtheKdevelopmentKofKaKUTI.KFinally,KindividualsKwhoKexperienceKurinary
Kobstruction,KdiabetesKorKneurogenicKbladderKareKalsoKatKriskKforKdeK-KANSWERK




UTIKRiskKFactors

ThereKareKseveralKriskKfactorsKthatKpredisposeKindividualsKtoKtheKdevelopmentKofKaKUTI.KForKwomen,Kpregn
ancyKisKaKriskKfactor.KDuringKpregnancy,KprogesteroneKrelaxesKsmoothKmuscleKthatKcausesKstasisKofKurine,Ka
llowingKtheKbacteriaKtoKcolonize.KAlso,KtheKfemaleKureterKisKshorterKandKallowsKforKtheKentranceKofKbacteri
aKintoKtheKurethra.

Post-
menopausalKwomenKareKalsoKatKriskKforKdevelopingKaKUTI.KTheKlackKofKestrogenKresultsKinKvaginalKandKuret
hralKdrynessKthatKpromotesKanKenvironmentKforKbacteriaKtoKgrow.KSexualKintercourseKalsoKcontributesKtoKt
heKdevelopmentKofKaKUTIKwhereKbacteriaKcanKbeKeasilyKintroducedKintoKtheKurethra.KIfKspermicidesKareKuse
dKduringKsexualKintercourse,KthisKalsoKputsKtheKwomanKatKriskKforKaKUTI.

IndwellingKurinaryKcatheterizationKisKalsoKaKmajorKcauseKofKaKUTI,KespeciallyKinKfemales.KTheKcatheterKitself
KcanKintroduceKinfectionsKdirectlyKintoKtheKbladder.KTheKbacteriaKwillKcoloniK-KANSWERK




LowerKvs.KUpperKTractKDisorders

,AKUTIKcanKbeKdiscussedKinKtermsKofKitsKlocation.KNoteKthatKaKUTIKcanKoccurKanywhereKalongKtheKurinaryKtra
ctKandKcanKbeKassociatedKwithKanotherKissueKinKtheKarea.KForKexample,KifKtheKinfectionKoccursKatKtheKopeni
ngKofKtheKurethra,KthenKtheKconditionKisKtermedKurethritis.KOverall,KcystitisKisKaKconditionKofKtheKlowerKurin
aryKtractKthatKdenotesKaKbladderKinfection.KCystitisKcanKoccurKinKbothKfemalesKandKmales.KInKmales,KtheKcys
titisKmayKbeKassociatedKwithKprostatitis.



RecognizingKtheKsignsKandKsymptomsKofKtheKUTIKisKimportantKinKcategorizingKitKasKeitherKaKlowerKorKupperK
urinaryKtractKdisorder.KInKaKlowerKurinaryKtractKdisorder,KtheKindividualKexperiencesKurgencyKassociatedKwit
hKburningKonKurination.KOtherKcommonKsymptomsKofKaKlowerKUTIKisKfrequency,Kdysuria,KandKsuprapubicKp
ain.KTheKurineKmayKalsoKappearKcloudyKandKhaveKanKodor.

AnKinfectionKofKtheKlowerKurinaryKtractKcanKprogressKtoKanK-KANSWERK



UncomplicatedKvs.KComplicatedKUrinaryKTractKInfectionsK(UTI)

AKUTIKmayKbeKclassifiedKasKcomplicatedKorKuncomplicatedKinKtermsKofKitsKseverity.KAnKuncomplicatedKUTIKi
ndicatesKthatKtheKurinaryKtractKandKrenalKfunctionKisKnormal.KInKaKcomplicatedKUTI,KthereKisKdecreasedKren
alKfunctionKandKanKabnormalKurinaryKtract.KInKdifferentiatingKbetweenKaKlowerKandKupperKUTIKabove,KtheKp
resenceKofKWBCKcastsKindicatesKtheKpresenceKofKkidneyKinvolvementKwhichKrequiresKaKmoreKcomplicatedKt
reatmentKplan.KTheKpatientKisKalsoKatKhigherKriskKforKextensiveKandKpermanentKkidneyKdamageKasKwellKasKs
epsis.KIfKsepsisKisKsuspected,KaKbloodKcultureKmayKbeKdrawnKtoKidentifyKtheKcausativeKorganismKorKruleKitKo
ut.

TheKseverityKofKtheKUTIKcanKalsoKbeKdeterminedKbasedKonKtheKinterventionsKthatKareKnecessaryKtoKtreatKth
eKinfection.KTheKmoreKinterventionKrequired,KtheKmoreKcomplicatedKtheKinfection.KInKgeneral,KindividualsKa
reKtreatedKforKaKUTIKonlyKwheK-KANSWERKUncomplicatedKUTI

OccursKinKtheKnormalKurinaryKtract

SimpleKcystitisKinKnon-pregnantKwomenKwithoutKanyKurologicKabnormalities

RespondsKwellKtoKaKshortKcourseKofKantibioticKtherapy



ComplicatedKUTI

AKUTIKthatKextendsKbeyondKtheKbladder

CausedKbyKstructuralKorKfunctionalKurinaryKtractKabnormalitiesKorKuntreatedKUTI

InfantsKandKolderKadultsKaffected

AssociatedKwith:

indwellingKcatheters

renalKcalculi

, Diabetes

Pregnancy



CommonKOrganismsKthatKCauseKUrinaryKTractKInfections

TheKmostKcommonKorganismsKthatKcauseKaKUTIKisKEscherichiaKcoliK(E.KColi),KStaphylococcusKsaprophyticus,K
ProteusKMirabilis,KandKKlebsiella.KE.KcoliKcausesKapproximatelyK80%KofKtheKcasesKofKUTIKbecauseKitKisKtheKm
ostKcommonKorganismKcontainedKinKtheKfecalKmatterKthatKisKeasilyKaccessibleKfromKtheKanusKtoKtheKurethra
.KBacteriaKenterKtheKurethraKandKcolonizeKinKtheKbladderKtoKeventuallyKcauseKaKUTI.KInKhealthyKindividuals,K
theyKcanKmaintainKaKsterileKurinaryKtractKandKbladder.KEvenKwhenKbacteriaKenterKtheKbladder,KtheKimmuneK
defensesKcanKpreventKitKfromKclingingKtoKtheKwallsKofKtheKbladderKorKtheKupperKurinaryKtract.KAKUTIKwillKocc
urKwhenKbacteriaKoverwhelmKtheKindividual'sKdefenseKmechanismsKallowingKitKtoKquicklyKreproduce.

AKurinalysisKisKusedKtoKdiagnoseKaKUTI.KIfKnitritesKareKpresent,KthisKindicatesKthatKtheKcausativeKorganismKisK
gramKnegative.KAKurineKcultureKmayK-KANSWERK



UsingKtheKUrinalysisKtoKDiagnoseKaKUrinaryKTractKInfection

AKurinalysisKcanKbeKusedKinKaKcoupleKofKwaysKtoKdiagnosisKaKUTI.KAKdipstickKcanKbeKusedKtoKidentifyKleukocy
teKesteraseKandKnitrites.KNitritesKdetectKtheKpresenceKofKtheKEnterobacteriaceaeK(gramKnegativeKbacteria)K
familyKthatKconvertsKnitratesKintoKnitrites.KItKisKimportantKtoKalsoKnoteKthatKsomeKbacteriaKareKunableKtoKpr
oduceKnitrites.KThisKisKtheKcaseKofKEnterococcus.KTherefore,KtheKindividualKmayKstillKhaveKaKUTIKevenKifKnitri
tesKareKnotKpresentKviaKtheKdipstick.KTheKpresenceKofKnitritesKisKtheKmostKspecificKfindingKandKhasKtheKhigh
estKpositiveKpredictiveKvalue.

LeukocyteKesterase,KWBCsKandKevenKbacteriaKonKmicroscopicKexamKareKnotKspecificKandKtherefore,KdoKnotK
necessarilyKindicateKinfection.KTheKdiagnosisKofKaKUTIKneedsKtoKalsoKconsiderKtheKpresenceKofKsymptomsKa
ndKaKpositiveKurineKcultureKifKoneKisKcompleted.KItKisKtypicallyKnotKcompletedKinKaKyoung,KandK-KANSWERK



PatientKEducation

TheKNPKshouldKtakeKadvantageKofKtheKopportunityKtoKeducateKpatientsKonKtheKpreventionKofKUTIsKwhileKth
eKpatientKisKinKtheKoffice.KSomeKofKtheKmostKbasicKinformationKtoKconveyKtoKaKpatientKis:

DrinkKmoreKwater.

AlthoughKthereKareKdifferencesKofKopinions,KcranberryKjuiceKandKvitaminKCKcanKhelpKtoKacidifyKtheKurine.

UrinateKbeforeKandKafterKsexualKintercourseKtoKremoveKbacteriaKfromKtheKurethralKarea.

EncourageKtheKfemaleKtoKavoidKholdingKurineKforKextendedKperiodsKofKtime.

AvoidKtheKuseKofKhygieneKspraysKandKspermicidesKbecauseKtheyKalterKtheKnormalKmicrobialKfloraKtoKenhanc
eKtheKriskKforKinfection.

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