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PMCOL 300 Midterm Drugs Exam Latest Update
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PMCOL 300 Midterm Drugs ExamLatest Update
Diethyl Ether (Ether) - Answer anesthetic
GABAA neurotransmitter
stimulates GABAA (which inhibits CNS)
Loss of feeling
- slow induction/recovery (high partition coefficient)
Nitrous Oxide - Answer anesthetic
GABAA neurotransmitter
stimulates GABAA (which inhibits CNS)
Loss of feeling
- low blood solubility → very high MAC
- hard to store
- commonly used in dentistry
- given at stage 3
- no large meals 3 hours before administration
Halothane - Answer anesthetic
GABAA neurotransmitter
stimulates GABAA (which inhibits CNS)
Loss of feeling
- moderate blood solubility (moderate induction)
- very potent (MAC = 0.75%)
- hepatitis can occur, but rare (liver inflammation)
Isoflurane - Answer anesthetic
GABAA neurotransmitter
, stimulates GABAA (which inhibits CNS)
Loss of feeling
- pungent smell
- low blood solubility (rapid induction)
- potent (MAC = 1.2%)
- same family as "desflurane" → new halogenated ether
Barbiturates - Answer anesthetic
GABAA neurotransmitter
stimulates GABAA (which inhibits CNS)
Loss of feeling
- very short acting (very rapid induction)
- given at stage 1
- is redistributed from the brain to other tissues quickly → can be used for very short
dental procedures
- pt will pass from stage 1 right to stage 3 (no analgesia during the switch)
Ketamine - Answer dissociative
anesthetic
NMDA receptor
Antagonist for NMDA receptor (stops it)
Loss of feeling (but no loss of consciousness)
- rapid onset
- causes delirium & hallucinations upon recover
Morphine - Answer Analgesic
Opioid receptor (Mu)
Agonist for opioid receptor
Loss of pain
The prototype opioid agonist that all other opioids are measure to
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