NURS 5334 EXAM 3 (MODULE 6)2024-2025
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Which medication is better for the liver and has a lesser chance of Hepatotoxicity?
A. Methimazole
B. PTU
Methimazole
What is the most serious side effect of Methimazole?
A. Agranulocytosis
B. Hepatotoxicity
C. Cardiac Arrhythmias
D. Osteoporosis
A. Agranulocytosis
What is the MOA of Radioactive Iodine?
Emits beta energy particles and destroys thyroid function, reducing the production of thyroid hormone
Medication such as Methimazole and PTU should be discontinued prior to initiating Radioactive Iodine
therapy, True or False?
True, done to increase the efficiency of I-131
Clarissa has hyperthyroidism and need to initiate treatment to reduce her thyroid production. The NP
wanted to initiate Radioactive Iodine therapy due to its low cost, low risk of death and non invasive
nature. What must be done first prior to initiating treatment?
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,Pregnancy test
I-131 is contraindicated for all that are pregnant or breastfeeding
Which Beta blocker decreases the effects of Thyroid hormone?
Propranolol
How does Prednisolone affect thyroid hormone?
Inhibits the conversion of T4 to T3
What's the MOA of Lugol's solution?
Lugo's solution contains iodine and potassium iodide, this inhibit release of thyroid hormones by
saturating the thyroid gland with iodine
Lugol's solution is First or Second line treatment of thyroid storm?
Second line treatment for Thyroid Storm
Identify the symptoms of Congenital Hypothyroidism in newborns: (SATA)
A. Protruding tongue
B. Potbelly
C. Hypoactivity
D. Dwarfish Stature
E. Excessive Sweating
A, B, D
What effect does estrogen have on cholesterol?
increases HDL and decreases LDL
What effect does estrogen have on coagulation?
Increased levels of coagulation factors
What effect does estrogen have on glucose?
Estrogen is shown to increase glucose sensitivity and promote glucose uptake
What are three drawbacks (adverse effects) of SERMS?
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, Hot flashes
Endometrial cancer
Thromboembolism
Estrogen can help protect against Osteoporosis, True or False?
True
What is the MOA of Tamoxifen?
Antagonist of estrogen receptor on breast tissue. Inhibiting the growth of Breast cancer tissue.
Tamoxifen can protect against Osteoporosis, True or False?
True
Tamoxifen use increases risk for what type of cancer?
Endometrial Cancer
What is the difference between Tamoxifen and Raloxifene?
Tomoxifen: ER antagonist at breast, agonist at bone, uterus
Raloxifene: antagonist at breast, uterus; agonist at bone - no increased risk of endometrial cancer; used
primarily for osteoporosis
What's the medication of choice for Osteoporosis?
Raloxifene
What is the primary therapeutic use of Hormone Therapy (HT) in postmenopausal women?
Treatment of moderate to severe vasomotor symptoms
Bazedoxifene (Duavee) is a combination of what two thing?
Estrogen plus a Estrogen Agonist/Antagonist
What is the therapeutic use of Bazedoxifene?
Reduce vasomotor symptoms in postmenopausal women
You should use Bazedoxifene for as long as possible, True or False?
False, drug should be used for as short duration as possible due to risk of excessive growth of the
uterine lining posted by the estrogen component
Mifepristone (RU-486) is combined with what medication to induce medical abortion?
Misoprostol
How does Mifepristone and Misoprostol induce medical abortion?
The combination induced medical abortion by causing uterine contractions
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