Nur 211 Exam 3 Review Questions and
Correct Answers
Sickle cell anemia predisposition ✅African american
Central africa
The near east
Mediterranean
Aboriginals
Hispanics (caribbean, central and south america)
Sickle cell anemia clinical manifestations ✅Fatigue
Weakness
Pain
Swelling
Tachycardia
Murmur
Enlargement of bones in face and skull
Sickle cell how to diagnosis ✅CBC - low hematocrit
Hgb electrophoresis
What is sickle cell acute Vaso-occlusive crisis? ✅Very painful, rbc and WBC
entrapment causing tissue hypoxia, inflammation, and necrosis due to inadequate blood
flow
What is sickle cell aplastic crisis? ✅Due to parvovirus, rapid fall in HgB were bone
marrow cannot compensate
What is sickle cell sequestration crisis? ✅Other organs (specifically spleen) affected by
pooling of sickle cells
What triggers a sickle cell crisis? ✅Illness
Stress
Alcohol
Dehydration
Cold weather
High altitude
Complications of sickle cell anemia ✅Anemia, Pulmonary hypertension, Acute chest
syndrome, heart/renal failure, CVA/Stroke, infection, leg ulcers, eye damage, substance
abuse
, How do you treat sickle cell anemia? ✅Management of symptoms, therapies (rx,
procedural, supportive)
What are procedural therapies to treat sickle cell anemia? ✅Hematopoietic stem cell
transplantation, transcranial doppler studies
What RX therapy is used to treat sickle cell anemia? ✅Hydroxyurea
Nsaids
Morphine
Opioids
Antibiotics (pcn)
Corticosteroids
What class of drugs is hydroxyurea to treat sickle cell anemia ✅Antineoplastic
What is the typical dose for sickle cell patients using hydroxyurea? ✅15-35mg/kg/day
How does hydroxyurea work for sickle cell anemia? ✅Increases fetal hgb in children,
decreased number of circulating lymphocytes, decreases pain with crisis
What are the adverse reactions associated with hydroxyurea used for sickle cell
disease? ✅Thrombocytopenia
Leukopenia
What are nursing roles while using hydroxyurea for sickle cell anemia? ✅Monitor CBC,
fevers, do not crush/open, avoid handling, use caution, drink plenty of fluids, avoid
pregnancy
What action does morphine have with sickle cell anemia crisis? ✅Drug of choice.
Relieves pain, dosing individualized, generally given IV during crisis
What side effects does morphine have while using for sickle cell anemia crisis?
✅Sedation, respiratory depression, constipation, urinary retention
What are the supportive therapies used for sickle cell anemia? ✅Blood transfusions,
oxygen, hydration, rest, nutrition
What nursing management/assessment is used for sickle cell anemia? ✅Assess prior
treatment, precipitating factors, assess all body systems (joints, pain, swelling, lung
sounds, o2 says, edema, circulation, LOC, leg ulcers, skin turgid), monitor s/s infection,
I&O for dehydration
