Exam- Advanced patho N5315 Endocrine module 8 Test
Questions and Answers
what are the hormones of the thyroid? Correct--regulated by TSH from anterior pituitary:
the uptake of iodine is regulated by TSH
-T4 (90%) and T3 (10%)
-Thyroxine (used with 1mg/wk of iodine)
-A low level of thyroid hormone
stimulates the release of thyroid-releasing factor, stimulates the release of TSH, then
stimulates the thyroid to release more T3 and T4
What are the actions of the thyroid hormones? Correct--TH levels rise--negative feedback
loop on HPA--- to inhibit TRS and TSH
-increase metabolism
-maintenance of muscle tone, skeletal muscle maturation; antagonization of insulin;
regulation of cellular metabolism; promotion of the production of heat; maintenance of
cardiac output, contraction and rate; maintenance of GI secretion; assistance with calcium
mobilization and stimulation of lipid metabolism; free fatty acid release; cholesterol
synthesis;skeletal muscle maturation; antagonization of insulin; regulation of cellular
metabolism; promotion of the production of heat; maintenance of cardiac output,
, Exam- Advanced patho N5315 Endocrine module 8 Test
Questions and Answers
contraction and rate; maintenance of GI secretion; assistance with calcium mobilization and
stimulation of lipid metabolism; free fatty acid release; cholesterol synthesis
Thyroid hormone effects on the heart Correct-The production of the contractile protein α-
myosin heavy chain is stimulated by T3 in the
heart. T3 also stimulates the production of the sarcolemma ion pumps (Na+-K+ ATPase
pump, Ca++ ATPase pump) and the β-adrenergic receptors.
What does calcitonin do? Correct-Calcitonin is secreted by the C-cells of the thyroid. It
functions to lower serum calcium by preventing the bone resorption effects of PTH,
prostaglandins and calciferols by blocking osteoclastic activity. It is also responsible for
lowering serum phosphate levels and decreasing GI absorption of calcium and phosphorus
What are the hormones of the pancreas? Correct--alpha cells secrete glucagon
-beta cells secrete gastrin
-delta cells secrete gastrin and somatostatin
-F cells secrete pancreatic polypeptide that stimulates the secretion of gastric acid and
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