RED BLOOD CELLS
Erythropoietin - ANS hormone secreted by kidneys for the formation of RBCs----
released during anemia
Splenic contraction - ANS significant, allows horses to have more speed, rbc
stored here, circulate in spleen, cause fight or flight response, RBC can be
damaged here
RBC function - ANS transports O2 from the lungs to the tissues and carbon
dioxide from tissues to lungs
hemoglobin - ANS iron-containing protein in red blood cells that carries oxygen
for delivery to cells
methemoglobin - ANS An altered hemoglobin which does not carry
oxygen.before the liver can convert back to hemoglobin
MCV - ANS Mean corpuscular volume average volume of RBCs; useful for
anemia classification
MCH - ANS mean corpuscular hemoglobin
MCHC - ANS mean corpuscular hemoglobin concentration
erythropoiesis - ANS the process of producing red blood cells by the stem cells
in the bone marrow
Fibroblasts - ANS Step 1 large solid nucleus w/ little cyto (stains guite dark), for
every stem cell, there is one of these cells, split into 2 pro rubricytes
Prorubricyte - ANS Step 2 : 2 cells form from the division of a rubriblast (cell size
dec., nucleus size decreases, (cytoplasm matures and becomes lighter) has to
end up w/ no nucleus
, Rubricyte - ANS Step 3. in the RBC pathway. Cell undergoes 3 mitotic divisions.
Cell size decreases, nuclear size decreases, and cytoplasm matures.
Metarubricyte - ANS Step 4. and contains a very dense nucleus (nRBC)
57%-67% - ANS What percent in a dz animal where there are metarubricytes?
Erythrocyte - ANS a mature blood cell that contains hemoglobin to carry oxygen
to the bodily tissues
Platelets - ANS thrombocytes; cell fragments in the blood essential for blood
clotting (coagulation)
Megakaryoblasts - ANS build mature platelets
Anisocytosis - ANS Unequal sized RBCs
polychromasia - ANS condition of many colors; clinically means erythrocytes
with varies or multicolored staining qualities
hypochromasia - ANS No color in cell due to insufficient Hb within the cell. Low
Iron.
Discocyte - ANS Biconcave Disc, normal RBC
Normocytic - ANS A normal sized Erythrocyte....
normochromic - ANS pertaining to normal concentration of hemoglobin (colour)
Microcytosis - ANS Small RBCs, anemia with decreased MCV, observed normal
in Asian dogs
Macrocytosis - ANS A condition anemia where there is interference with nucleic
acid synthesis inhibiting cell division (vitamin B12 / folic acid def)min. poodles
and malamutes and the cell is bigger.
hypochromia - ANS red blood cells that have a decreased red color, iron
deficiency, lead toxicity
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