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RBC ANOMALIES EXAM QUESTIONS AND ANSWERS 2024/2025( A+ GRADED 100% VERIFIED).
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RBC ANOMALIES EXAM QUESTIONS AND ANSWERS 2024/2025( A+ GRADED 100% VERIFIED).
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RBC ANOMALIESAnemia - ANS • Decreased in the oxygen-carrying capacity of the blood.
• Reduction in the hemoglobin content of the blood that can be caused by
decreased RBCS, hemoglobin, and hematocrit below reference levels.
MECHAN
ineffective erythropoiesis - ANS production of erythroid cells that are ineffective.
Megaloblastic anemia - ANS deficient DNA synthesis due to vitamin B12 or folate
acid
thalassemia - ANS Deficient globin chain
•••
LAB DIAGNOSIS
complete blood count reticulocyte count peripheral blood smear
§ can observe the following hemoglobin content:
o hyperchromic, hypochromic, normochromic
§ cell size/RBC diameter:
o microcytic, macrocytic, normocytic = RBC
indices
RBC ANOMALIES
variation in hemoglobin content
hypochromic RBC
central light area of the cell is larger and paler than the normal
6-8 um
synthesis
Sideroblastic anemia - ANS deficient protoporphyrin synthesis
Insufficient erythropoiesis - ANS decrease in the number of erythroid precursors
in the bone marrow resulting in decreased RBC production and anemia.
autoimmune reaction - ANS loss of the erythroid precursors due to an
traumatic injury - ANS acute blood loss
, intermittent bleeding - ANS chronic blood loss
complete blood count, reticulocyte count, peripheral blood smear - ANS what are
the lab diagnosis?
hyperchromic, hypochromic, normochromic - ANS can observe the following
hemoglobin content:
cell size/RBC diameter - ANS microcytic, macrocytic, normocytic = RBC
indices
RBC Anomalies - ANS - variation in hemoglobin content
- hypochromic RBC
- central light area of the cell is larger and paler than the normal
- 6-8 um
seen in:
IDA, thalassemia, posthemorrhagic anemia, parasitism, malignancy.
HYPOCHROMIC RBC - ANS The central light area of the cell is larger and paler
than the normal
seen in: IDA, thalassemia, post-hemorrhagic anemia, parasitism, malignancy.
HYPERCHROMIC RBC - ANS - central pallor is smaller than normal or
nonexistent: RBC with seemingly increased hemoglobin content.
seen in: hereditary spherocytosis, and in cases of megaloblastic anemia.
POLYCHROMATIC RBC - ANS Cell stained with various shades of blue with
tinges of pink due to the combined affinity of Hb to acid dye and that of RNA to
the basic dye.
seen in: Reticulocytosis, hemolysis, acute blood loss, pernicious anemia.
pernicious anemia - ANS deficiency in intrinsic factor (produced by the stomach,
stored by the liver) (cannot absorb Vit b12 if there's no intrinsic factor)
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