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MIP 260 Study Test | Questions with 100% Correct Answers
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MIP 260 Study Test | Questions with100% Correct Answers
heteroxenous - ✔✔part of life spent in vertebrate blood or tissues and part spent
in intestine of blood ducking arthropods
life stages of trypan - ✔✔trypomastigote in vertebrate host and epimastigote
in insect host
amastigote: 2-3 microns and a short flagella
promastigote- inesct host, anterior flagella
trypansome cruzi - ✔✔chagas disease, life cycle- tsetse fly bites human,
trypamastigote in blood stream, taken up by another bug, transforms into epimastigote,
start again, found in us, 14 species of mammals infected, reservoirs eat infected bugs
trypansoma brucei brucei - ✔✔affects horses, mules, donkeys, dogs, camels (nto
humans), causes edema, fever. watery eyes, anemia, paralysis, death may occur in
2 weeks to 4 months
clinical signs of african sleeping sickness - ✔✔chancre at bite site, intermittent
fever, headaches, extreme fatigue, progressive confusion, personality chnages, swollen
nodes at the abse of the skull
, varient surface glycoprotein coat - ✔✔vsg covers the entire organism (a barrier
to antibodies), osicallte between being VSG+ and -, evades the immune system
clinical signs of chagas disease - ✔✔acute form- small red nodule, lymph
node swelling, chills, muscle and bone pain, enlarged liver and spleen, cardiac
failure, common and sever in children
chronic form- central nervous system dysfunction, enlarged esophagus and colon,
cardiac failure
leishmania - ✔✔heteroxenous, over 23 species and subspecies, sandfly vector,
arthropod vector - promastigote (infectious), amastigotes in vertebrate tissue
(humans, dogs, and rodents), smallest nucleated cells known in this stage
wjat is one of the most puzzling immunological questions - ✔✔how leishmania
lives inside macrophages
leishmania life cycle - ✔✔sandfly rakes a blood meal, promastigote phagocytize by
macrophages, transforms into amastigote, sandfly rakes a blood meal, transforms into
promastigote, repeat
cutaneous form of leishmania - ✔✔topical and major and mexicana, cutaenous
ulcers, small red pauple but then a thin crust develops over the ulcer, can coalesce into
a sore, can heal but will leave large depressed unpigmented scars, secondary
infections are common, dry lesions can persist for months
diagnosis of leishmanaia - ✔✔scraping from edge of ulcer and then stained
mucocutaenous form of leismania - ✔✔braziliensis, central mexico and
norther argentina, flat ulcerated plaques
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