MIP302 Final Exam Study Guide
chemotherapeutic agents - Answer️️ -chemicals administered internally to the host for
the control of microbial infections; used to control fungal, protozoal, and bacterial
infections
Bacteriocidal - Answer️️ -agent that kills bacteria
Bacteriostatic - Answ...
inhibition of cell wall synthesis (antibiotics) - Answer✔️✔️-prevents synthesis of
peptidoglycan by binding to certain enzymes thus preventing peptide interbridges
between NAG and NAM from forming; cells undergo lysis
what type of antibiotics use inhibition of cell wall synthesis as their mechanism? -
Answer✔️✔️-penicillin, vancomycin, and others
inhibition of protein synthesis (antibiotics) - Answer✔️✔️-some bind to 30S ribosomal
subunit, either causing incorrect translation of mRNA transcript or interfere with
aminoacyl-tRNA binding
others bind to the 50S subunit and prevent peptide bond formation and peptide chain
elongation
what type of antibiotics use inhibition of protein synthesis as their mechanism? -
Answer✔️✔️-target 30S: streptomycin, gentamicin, chloramphenicol, and tetracycline
target 50S: chloramphenicol, erythromycin, and clindamycin
inhibition of nucleic acid synthesis (antibiotics) - Answer✔️✔️-inhibit bacterial DNA gyrase
to interrupt DNA replication and transcription OR may bind to DNA-dependent-RNA-
polymerase (blocks RNA synthesis)
what type of antibiotics use inhibition of nucleic acid synthesis as their mechanism? -
Answer✔️✔️-ciprofloxacin, norfloxacin, ofloxacin, and rifampin
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