EXAM WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS CURRENTLY TESTING EXAM
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Key Elements of a Prescription - ANSWER-1) Prescriber Name
2) License Number
3) Contact Information
4) DEA number of prescriber and supervising physician
5) Patient Name
6) Patient DOB
7) Patient Allergies
8) Name of Medication
9) Indication for Medication
10) Strength of Medication
,11) Dosing Frequency
12) Number of tablets/capsules to disepense
13) Number of refills
14) SIG or instructions for the prescription (E.g. "Take one tablet by mouth daily")
3 primary reasons for drug monitoring - ANSWER-1) determine therapeutic dosage
2) evaluating medication adequacy: desired effect achieved
3) identifying adverse effects: presence of patient harm
Pharmacokinetics - ANSWER-Study of drug movement throughout the body
Includes drug metabolism and excretion
Passage across cell membrane
Absorption - ANSWER-Drug's movement from site of administration to the blood
Rate=how soon effects begin
Amount=how intense the effects will be
, Rate of absorption depends on - ANSWER-rate of dissolution
surface area
blood flow
lipid solubility
pH partitioning
Distribution - ANSWER-Drug's movement from blood into interstitial space and then into cells
Metabolism - ANSWER-"Biotransformation"
Enzyme mediated alteration of the drug structure
Excretion - ANSWER-How drugs and metabolites move out of the body
Elimination - ANSWER-combination of metabolism and excretion
Movement of drugs - ANSWER-GI Tract/Site of administration-->Blood-->Liver/Kidney/Site of action/Other
Sites-->Bile/Urine-->Outside of body
3 ways for drugs to cross cell membrane - ANSWER-1) Channels and pores
2) Transport systems (P-glycoprotein)
3) Direct penetration of the membrane - **Most common**