CMB2001 Questions and Answer | Latest Update 2024/2025
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Course
CMB2001
Institution
CMB2001
Core Promoter Elements
~~> TATA box = repetitive sequence of thymine and adenine
Initiator (INR) = sequence of pyramidines like thymine and cytosine
DPE = downstream promoter elements found along the DNA
Common to have >1 promoter but not all of them
CpG islands
~~> Sequences hig...
✓ ~~> D -> A -> B -> F + RNA polymerase II -> E + H
CTD on RNA polymerase II
✓ ~~> C-terminus domain on beta' subunit is highly phosphorylated
during transcription
TFII fate during transcription
✓ ~~> - TFII D and A remain at the promoter site
- TFIIF remains with the RNA polymerase II
- TFII H, E and B
TFIIA
✓ ~~> Promotes binding of TFIID and has antirepressing function
TFIIB
✓ ~~> Recruits RNA polymerase II and TFIIF so is important for start site
selection
TFIID
Master01 | September, 2024/2025 | Latest update
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