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College Homeostase Regulatie en Integratie
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Regulatie en Integratie College Homeostase
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Homeostasis of body fluidsRegulatie en Integratie
Vrouwen bevatten minder water dan mannen,
omdat mannen meer spieren hebben. Water
percentage hangt af van de hoeveelheid vet.
Meer vet is minder water.
Plasma 3 L
Interstitiële vloeistof 11 L
Intracellulaire vloeistof 28 L
Bij een man van 70 kg bevat het lichaam dus
60% water = 42 L.
Extracellulair = 1/3, intracellulair = 2/3
De samenstelling van plasma en
interstitiële vloeistof is ongeveer
hetzelfde.
Bloedcirculatie bestaat uit 3 L
plasma en 2 L bloedcellen.
Molariteit 1 mol = 6x1023 moleculen mol/l mmol/l
Equivalent mol x valency eq/l meq/l
Osmolariteit hoeveelheid mol per liter osmol/l mosmol/l
Hoeveelheid mol/kg osmol/kg mosmol/kg
1 mol/l NACl = 2 osmol/l = 2 eq/l
1 mol/l Na+ = 1 osmol/l = 1 eq/l
1 mol/l Ca2+ = 1 osmol/l = 2 eq/l
D x A x ΔCC
Diffusie is de random thermal motion van moleculen. Diffusional flux J =
d
Osmose is de diffusie van water. Water wordt nooit actief getransporteerd, altijd passief. Het gaat
van een hoge concentratie naar een lage concentratie. 1 mosmol verschil osmotische druk = 19,3
mm Hg.
Tonicity bepaalt de osmotische flow van water door het celmembraan.
Hypotonic cel zwelt
Isotonic volume van de cel verandert niet
Hypertonoic cel krimpt
De normale omgeving van de cel is 280 mOsm/L
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