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OCN exam 100% Correct!!
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Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the electrical conduction within the heart. 2. cardiomyopathy as the most common chronic cardiac toxicity Asymptomati...

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  • September 16, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • ocn exam 100 correct
  • ocn exam 100 correct stuvia
  • pegfilgrastim neulasta answer1 dose each cycle
  • asymptomatic bradycardia is likely to related to w

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OCN exam 100% Correct!!

Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo



Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the
electrical conduction within the heart.

2. cardiomyopathy as the most common chronic cardiac toxicity



Asymptomatic bradycardia is likely to related to which of the following chemo agents - ANSWERPaclitaxel
(Paxen, Taxol)



Factors that are associated with increased risk of cardiotoxicity from chemo include - ANSWER1 high-
dose cyclophosphamide, RT to the chest, and multiple cardiotoxic drugs

2. high doses o potentially cardiotoxic chemo agents administered over relatively short periods of time.



Prevention of doxorubicin related cardiomyopathy includes - ANSWERexercise ad use of dexrazoxane



When the ejection fraction is less than 45% the nurse should expect - ANSWERdecrease in the dose of
cardiotoxic chemo agents



Which statements correctly identify the classification of chemo agents and their potential effects -
ANSWER1 Antimetabolites have the potential to cause coronary artery spasm, resulting in cardiac
related sudden death

2 Taxanes and some alkylating agents can cause early heart failure and left ventricular dysfunction



A client admitted with CHF. Records indicate hx of breast cancer treated with chemo and RT. The most
likely late effect of this treatment is - ANSWERcardiomyopathy caused by anthracycline therapy



major difference between the short acting and intermidiate and long acting corticosterioids -
ANSWERShort acting have greater sodium and water retention activity.

The major advantage of intermediate-

, acting corticosteroids is that they have minimal sodium- retaining activity; long-acting corticosteroids
have no sodium-retaining activity.



meperidine (demerol)-phenytoin (Dilantin) drug interaction - ANSWERreduced plasma levels of
meperidine



onset of action of fentanyl - ANSWERIV - 5-6 mins

Patch - 18-24 hours

Buccal 5-15 minutes



patient with brain mets may need to receive prophylactic phenytoin (dilantin) if receiving -
ANSWERprochlorperazine and meperidine

*Use of prochlorperazine and meperidine may lower seizure threshold



anxiolytic discontinuation may have risk - ANSWERpsychosis, seizures and coma



common s/e of SSRI - ANSWERsexual dysfunction



needs seizure related concern - ANSWERifosfamide, high dose methotrexate and busulifan



oprolvekin - ANSWERgrowth factor that stimulates platelet growth

Oprelvekin is still being evaluated for use

in cancer treatment.

The Food and Drug Administration has approved it to reduce plate- let transfusions caused by low
platelet nadirs.

Allergies to the product are not regarded a common problem at this time

1 has not been shown to decrease mortality rates

2 high cost and significant toxicity limit its use

3 Thrombocytopenia is typically managed with platelet transfusion

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