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Exam (elaborations)

OCN exam 100% Correct!!

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Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the electrical conduction within the heart. 2. cardiomyopathy as the most common chronic cardiac toxicity Asymptomati...

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  • September 16, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • OCN
  • OCN
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nursingismylife
OCN exam 100% Correct!!

Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo



Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the
electrical conduction within the heart.

2. cardiomyopathy as the most common chronic cardiac toxicity



Asymptomatic bradycardia is likely to related to which of the following chemo agents - ANSWERPaclitaxel
(Paxen, Taxol)



Factors that are associated with increased risk of cardiotoxicity from chemo include - ANSWER1 high-
dose cyclophosphamide, RT to the chest, and multiple cardiotoxic drugs

2. high doses o potentially cardiotoxic chemo agents administered over relatively short periods of time.



Prevention of doxorubicin related cardiomyopathy includes - ANSWERexercise ad use of dexrazoxane



When the ejection fraction is less than 45% the nurse should expect - ANSWERdecrease in the dose of
cardiotoxic chemo agents



Which statements correctly identify the classification of chemo agents and their potential effects -
ANSWER1 Antimetabolites have the potential to cause coronary artery spasm, resulting in cardiac
related sudden death

2 Taxanes and some alkylating agents can cause early heart failure and left ventricular dysfunction



A client admitted with CHF. Records indicate hx of breast cancer treated with chemo and RT. The most
likely late effect of this treatment is - ANSWERcardiomyopathy caused by anthracycline therapy



major difference between the short acting and intermidiate and long acting corticosterioids -
ANSWERShort acting have greater sodium and water retention activity.

The major advantage of intermediate-

, which of the following places anticancer drugs appropriately in terms of emetogenic potential?

1 . paclitaxel, ifosfomide greater than 2g/m2, and bulsufan - moderate

2. vinorelbine, vincristine and etoposide - low

3. bleomycin, docetaxel and melphalan - very low

4. Dacarbazine and doxorubicin/cyclophoasmide high - ANSWER4



One reason for administering 20mg of IV dex before chemo regimen - paclitaxel and carboplatin is to:

1. prevent allergic reaction to cisplatin

2. stimulate appetite after chemo

3. improve antiemetic efficacy

4. decrease the chance of chemo induced diarrhea - ANSWER3



Docetaxel, Paclitaxel - ANSWERdex given to prevent hypersensitivity



Effect antiemetic regimen for Doxorubicin and Cisplatin - ANSWER5 HT3 antigonist plus dexamethasone
and sometimes P-neurokinin-1



The serotonin antagonists include - ANSWERondansetron

(Zofran), granisetron, dolasetron, and palonosetron; they are antagonists,.



D2 antagonist - ANSWERProchlorperazine

metoclopramide and phenothiazines

Extrapyramidal s/e



NK-1 antagonist - ANSWERAprepitant

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