Exam (elaborations)
MCMP 422 Exam 3 Concepts
- Course
- Institution
MCMP 422 Exam 3 Concepts ...
[Show more]
Content preview
MCMP 422 Exam 3 Concepts 2024-2025primary immune response-Provides antibody-secreting B cells and effector T cells that
eliminate the infection
protective immunity-Antibodies produced during a primary response bind to and
neutralize the pathogen before it can initiate infection and spread
long-lived plasma cells (LLPCs)-Remain in the bone marrow and continue to produce
small amounts of antibody - sometimes for life -
memory cells Answer provide a much faster and more potent immune response during a
second exposure
secondary immune response Answer second exposure to a pathogen that uses memory
cells to fight off the infection
memory B cell - Response from the B cells that made the best antibody; has already
undergone somatic mutation, affinity maturation and isotype switching; expresses more
MHC II so cognate interaction with T helper cells is stronger
CD45RO - Response on the memory T cells and functions more efficiently with the T-cell
receptor and co-receptors, excludes the A,B,C exons
Central memory T cells Tcm- express CCR7 and L-selectin that confer their ability to
migrate in secondary lymph nodes and to interact with dendritic cells.
Effector memory T cells Tem- devoid of CCR7 and L-selectin migrate into tissues where
they rapidly respond against foreign antigens.
, Tissue resident memory T cells Trm- are resident in tissues where the initial infections
occurred.
original antigenic sin-Answer First virus strain limits future responses to other strains
active immunization-Answer exposure to infectious organism or antigens from an
infectious organism to generate an immunological memory to repel any later invasions
by the same organism
inactivated (killed) virus-Answer virus treated with heat or irradiation or chemicals so it
cannot replicate further, must be injected
live-attenuated virus - Answer live virus mutated so that it doesn't grow very well in
human cells
subunit vaccine - Answer a component of the virus is used as an antigen for the
production of neutralizing antibodies
BCG vaccine - Answer used to provide protection from tuberculosis (not used in the US)
vaccines against secreted toxins - Answer developed by purifying the toxin and
denaturing it (treat with formalin)
toxoid - Answer denatured toxin
conjugate vaccines - Answer formed by coupling bacterial capsule polysaccharides to a
toxoid
adjuvant - Answer Substance that enhances the immune response to antigens
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Easton. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
82215 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now