Autoimmunity ✔✔ANSWER✔✔reaction of immune response to one's own tissues
Tolerance ✔✔ANSWER✔✔self-antigens not normally seen by the immune system
Most common autoimmune disease ✔✔ANSWER✔✔Systemic lupus erythematosus (SLE)
Type 1 DM, MS, RA ✔✔ANSWER✔✔notable autoimmune diseases
SLE ✔✔ANSWER✔✔chronic autoimmune inflammatory disease that affects many body systems- more
women then men
Clinical Manifestations of SLE ✔✔ANSWER✔✔- arthralgias or arthritis
- vasculitis and rash
- renal disease
- hematologic changes, especially anemia
- cardiovascular disease
SLE Positive Labs ✔✔ANSWER✔✔ANA screen
Alloimmunity ✔✔ANSWER✔✔Immune reaction to tissues of another individual
x3 alloimmunity reactions ✔✔ANSWER✔✔transfusion reactions, transplant reactions, fetus during
pregnancy
Alloantigens ✔✔ANSWER✔✔nonself antigens from members of the same species
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