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INTERSTITIAL CYSTITIS EXAM 1 QUESTIONS AND ACCURATE ANSWERS
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INTERSTITIAL CYSTITIS EXAM 1 QUESTIONS ANDACCURATE ANSWERS
INTERSTITIAL CYSTITIS
Name - Answer Interstitial Cystitis / Bladder Pain Syndrome - abbreviated to IC/BPS
INTERSTITIAL CYSTITIS
Definition - Answer - (SUFU) An unpleasant sensation (pain, pressure, discomfort)
perceived to be related to the urinary bladder, associated with lower urinary tract
symptoms of more than 6 weeks duration, in the absence of infection or other
identifiable causes*
Bladder pain syndrome/interstitial cystitis is a clinically diagnosed condition and
includes chronic pelvic pain, which is often accentuated by bladder filling, accompanied
by urinary frequency. This condition serves as a diagnosis of exclusion; hence, no
particular test or marker diagnostic of the condition exists. IC is a chronic but treatable
inflammatory condition of the bladder characterized by recurring discomfort or pain in
the bladder and/or pelvic region.
Symptoms to include : voiding symptoms - frequency, urgency and/or pelvic pain IC is
also commonly referred to as painful bladder syndrome More recent studies have
uncovered that IC is significantly more common than initially believed Must have
increase in frequency as well as pain
The International Continence Society, or ICS, prefers the term painful bladder
syndrome, or PBS-Response The International Continence Society, or ICS, prefers
painful bladder syndrome, or PBS, defined as "the complaint of suprapubic pain related
to bladder filling, accompanied by other symptoms such as increased daytime and
night-time frequency, in the absence of proven urinary infection or other obvious
pathology"
Interstitial cystitis and allergies - Answer 40% of people with interstitial cystitis have
multiple allergies
, Physical Examination Findings - Answer - Bladder neck tenderness
- Suprapubic tenderness
- Levator ani tenderness
- Cervical motion tenderness
- Posterior vaginal tenderness
- Rectal tenderness
Have tenderness everywhere
Multiple Causes to Common Disease Presentation and Pathophysiology - Answer -
Infectious
- Genetic
- Neurogenic
- Autoimmune
- Mast Cell activation**
- Toxin
- Urine substance
- Bladder epithelial dysfunction1
- Decreased Bladder relaxation
Pathophysiology - Answer - What is the best circumstantial evidence for urine
abnormality?
- Pain and contraction of bowel segment are late in its course following substitution
cystoplasty (removing the bladder) and continent diversion
- Probably there is some substrate in the urine which gives rise to pain
Diagnosis - Answer - Initial evaluation includes frequency/volume chart, focused
physical examination, urinalysis and urine culture
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