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TEST BANK FOR Understanding Pathophysiology 6th Edition ilil ilil ilil ilil ilil ilil



By: Sue E. Huether; Kathryn L. McCance
ilil ilil ilil ilil ilil ilil ilil



www.answerdone.com
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TEST BANK FOR ilil ilil




Understanding Pathophysiology 6th Edition ilil ilil ilil



By: Sue E. Huether; Kathryn L. McCance
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PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
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Unit 1: The Cell
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Chapter 1: Cellular Biology ilil ilil ilil


Chapter 2. Genes and Genetic Diseases ilil ilil ilil ilil ilil


Chapter 3. Epigenetics and Disease (NEW)
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Chapter 4. Altered Cellular and Tissue
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Biology
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Chapter 5. Fluids and Electrolytes, Acids and Bases
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Unit 2: Mechanisms of Self-Defense
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Chapter 6. Innate Immunity: Inflammation and Wound Healing
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Chapter 7. Adaptive Immunity
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Chapter 8. Infection and Defects in Mechanisms of Defense
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Chapter 9. Stress and Disease
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Unit 3: Cellular Proliferation: Cancer
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Chapter 10. Biology of Cancer
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Chapter 11. Cancer Epidemiology
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Chapter 12. Cancer in Children and Adolescents
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PART TWO: BODY SYSTEMS AND DISEASES
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Unit 4: The Neurologic System
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Chapter 13. Structure and Function of the Neurologic System
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Chapter 14. Pain, Temperature, Sleep, and Sensory Function
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Chapter 15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function
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Chapter 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular
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Junction Chapter 17. Alterations of Neurologic Function in Children
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Unit 5: The Endocrine System
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Chapter 18. Mechanisms of Hormonal Regulation
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Chapter 19. Alterations of Hormonal Regulation
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Unit 6: The Hematologic System
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Chapter 20. Structure and Function of the Hematologic System
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Chapter 21. Alterations in Hematologic Function
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Chapter 22. Alterations of Hematologic Function in Children
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Unit 7: The Cardiovascular and Lymphatic Systems
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Chapter 23. Structure and Function of the Cardiovascular and Lymphatic Systems
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Chapter 24. Alterations of Cardiovascular Function
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Chapter 25. Alterations of Cardiovascular Function in Children
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Unit 8: The Pulmonary System
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Chapter 26. Structure and Function of the Pulmonary System
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Chapter 27. Alterations of Pulmonary Function
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Chapter 28. Alterations of Pulmonary Function in Children
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Unit 9: The Renal and Urologic Systems
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Chapter 29. Structure and Function of the Renal and Urologic Systems
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Chapter 30. Alterations of Renal and Urinary Tract Function
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Chapter 31. Alterations of Renal and Urinary Tract Function in Children
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Unit 10: The Reproductive Systems
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Chapter 32. Structure and Function of the Reproductive Systems
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Chapter 33. Alterations of the Female Reproductive System
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Chapter 34. Alterations of the Male Reproductive System
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Unit 11: The Digestive System
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Chapter 35. Structure and Function of the Digestive System
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Chapter 36. Alterations of Digestive Function
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Chapter 37. Alterations in Digestive Function in Children
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Unit 12: The Musculoskeletal and Integumentary Systems
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Chapter 38. Structure and Function of the Musculoskeletal System
ilil ilil ilil ilil ilil ilil ilil ilil


Chapter 39. Alterations of Musculoskeletal Function
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Chapter 40. Alterations of Musculoskeletal Function in Children
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Chapter 41. Structure, Function, and Disorders of the Integument
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Chapter 42. Alterations of the Integument in Children
ilil ilil ilil ilil ilil ilil ilil ilil

, TEST BANK FOR Understanding Pathophysiology 6th Edition
ilil ilil ilil ilil ilil ilil



By: Sue E. Huether; Kathryn L. McCance
ilil ilil ilil ilil ilil ilil ilil



www.answerdone.com
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Chapter 01: Cellular Biology
ilil ilil ilil




Huether& McCance: Understanding Pathophysiology,6th Edition
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MULTIPLE CHOICE ilil




1. A student is observing a cell under the microscope. It is observed to have supercoiled
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DNA with histones. Which of the following would also be observed by the student?
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



a. A single circular chromosome ilil ilil ilil



b. A nucleus ilil



c. Free-floating nuclear material ilil ilil



d. No organelles ilil




ANS: i l i l B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



nucleus; thus, the nucleus should be observed. A single circular chromosome called a
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



prokaryote contains free-floating nuclear material but has no organelles.
ilil ilil ilil ilil ilil ilil ilil ilil ilil




REF: p. 2 ilil ilil




2. A nurse is instructing the staff about cellular functions. Which cellular function is the
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



nurse describing when an isolated cell absorbs oxygen and uses it to transform nutrients to
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



energy?
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a. Metabolic absorption ilil



b. Communication
c. Secretion
d. Respiration
ANS: D ilil



The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



secretion allows for the synthesizing of new substances.
ilil ilil ilil ilil ilil ilil ilil ilil




REF: p. 2 ilil ilil




3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



of the genetic information be contained?
ilil ilil ilil ilil ilil ilil



a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm ilil




ANS: C ilil



The region of the cell that contains genetic material, including a large amount of ribonucleic
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



within the cell’s nucleus. Mitochondria is associated with cellular respiration, while
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



ribosomes are involved with protein manufacturing. Cytoplasm is a fluid filling that is a
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



component of the cell.
ilil ilil ilil ilil




REF: p. 2 ilil ilil

, TEST BANK FOR Understanding Pathophysiology 6th Edition
ilil ilil ilil ilil ilil ilil



By: Sue E. Huether; Kathryn L. McCance
ilil ilil ilil ilil ilil ilil ilil



www.answerdone.com
i l i l


4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving
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the layer itself?
ilil ilil ilil



a. Peripheral membrane proteins ilil ilil



b. Integral membrane proteins ilil ilil



c. Glycoproteins
d. Cell adhesion molecules ilil ilil




ANS: B ilil



Proteins directly attached to the membrane bilayer can be removed by the action of integral
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
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marks cells and does not float.
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REF: p. 7 ilil ilil




5. Which of the following can bind to plasma membrane receptors?
ilil ilil ilil ilil ilil ilil ilil ilil ilil



a. Oxygen
b. Ribosomes
c. Amphipathic lipids ilil



d. Ligands
ANS: D ilil



Ligands are the only specific molecules that can bind with receptors on the cell membrane.
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil




REF: p. 9 ilil ilil




6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil




uNp p oRr t t hIe dG
the extracellular matrix would sU iagnBo.
siC
s ofM
metastatic cancer?
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a.
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Decreased fibronectin
S N T O ilil
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ilil l
i ilil
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b. Increased collagen ilil



c. Decreased elastin ilil



d. Increased glycoproteins ilil




ANS: A ilil



Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
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them to travel or metastasize.
ilil ilil ilil ilil ilil




REF: p. 10 ilil ilil




7. Which form of cell communication is used to relate to other cells in direct physical contact?
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



a. Cell junction ilil



b. Gap junction ilil



c. Desmosome
d. Tight junction ilil




ANS: A ilil



Cell junctions hold cells together and permit molecules to pass from cell to cell.
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



Gap junctions allow for cellular communication between cells. Neither desmosomes nor
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



tight junctions are associated with cellular communication.
ilil ilil ilil ilil ilil ilil ilil




REF: p. 11 ilil ilil

, TEST BANK FOR Understanding Pathophysiology 6th Edition
ilil ilil ilil ilil ilil ilil



By: Sue E. Huether; Kathryn L. McCance
ilil ilil ilil ilil ilil ilil ilil



www.answerdone.com
i l i l


8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil il



alpha cells. This action is an example of which of the following signaling types?
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A ilil



Paracrine signaling involves the release of local chemical mediators that are quickly taken up,
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



glucagon. None of the other options involve signaling that is associated with a local chemical
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



mediator like insulin.
ilil ilil ilil




REF: p. 12 ilil ilil




9. In ilil cellular metabolism, each enzyme has a high affinity for a:
ilil ilil ilil ilil ilil ilil ilil ilil ilil



a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS: B ilil



Each enzyme has a high affinity for a substrate, a specific substance converted to a product
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



of the reaction. Cellular metabolism is not dependent on an attraction between an enzyme
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



and any of the remaining options.
ilil ilil ilil ilil ilil ilil




REF: p. 16 ilil ilil




10. An athlete runs a marathon, after which his muscles feel fatigued and unable to contract.
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



The athlete asks the nurse why this happened. The nurse’s response is based on the
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



knowledgethat the problem is result of a deficiency of:
ilil il ilil ilil ilil ilil ilil ilil ilil ilil



a. GTP
b. AMP
c. ATP
d. GMP
ANS: C ilil



When ATP is deficient, impaired muscle contraction results. None of the other options are
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



involved in muscle contraction.
ilil ilil ilil ilil




REF: p. 16 ilil ilil




11. Which phase of catabolism produces the most ATP?
ilil ilil ilil ilil ilil ilil ilil



a. Digestion
b. Glycolysis
c. Oxidation
d. Citric acid cycle ilil ilil




ANS: D ilil



While some ATP is produced during the oxidation and glycolysis phases, most of the ATP is
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil



generated during the citric acid cycle. Digestion does not produce any ATP.
ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil ilil

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